Amenorrhea

Updated: September 3, 2022

Background

Epidemiology

Anatomy

Pathophysiology

Etiology

Genetics

Prognostic Factors

Clinical History

Physical Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

Medication

medroxyprogesterone

5-10 mg orally each day for 5-10 days
Start over the therapy at anytime
Provera is only indicated for secondary amenorrhea caused due to imbalance of hormones
These when occurring due to the absence of organic pathologies like uterine cancer or fibroids
3-7 days later, the discontinuation of medroxyprogesterone

progesterone intravaginal gel

Administer 45 mg intravaginally every alternate day for six doses If there is no improvement, consider using 90 mg every alternate day for six doses

gonadorelin acetate

In Females:
Administer initial dose of 5 mcg through intravenous or subcutaneous every 90 minutes via suitable pulsatile pump
Dose modification may be done every three weeks, if necessary Treatment should be continued for 14 days after ovulation to maintain the corpus luteum

gonadorelin

Indicated for Primary hypothalamic amenorrhea
Initial dose: For females, 5 mcg intravenously or subcutaneously every 90 min through a suitable pulsatile pump
If required, dose adjustment can be made for every 21 days
If there is no response following three therapy intervals, an enhanced dosage is required

progesterone

Take a dose of 400 mg orally one time in at bedtime up to 10 days
Administer Dose of 45 mg vaginally in form of gel every alternate day

dydrogesterone

In combination with estrogen to prime endometrium
10mg or 20mg orally once daily from the 11th to the 25th day of menstrual cycle
Indications: It is indicated in treating secondary amenorrhea

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