Indicated for Post-Operative Period :

0.025-0.2 mcg/kg per minute IV

Indicated for Menstrual Cramps :

1-2 capsule/tablet/gelcap orally 4 times a day

Indicated for menstrual cramps:

1-2 caplets orally every 4-6 hours whenever necessary. Do not exceed eight caplets for 24 hours

Indicated for Analgesia for Minor Joint/ Muscle Pain:

Apply generous amounts topically and massage the affected region
Apply the patch to the affected area

For topical
Obtain standardized curcumin extract to 95%

Indicated for Analgesia for Minor Muscle/Joint Pain:

Apply a generous volume topically and massage the affected region three or four times daily

Indicated for Analgesic/Antipyretic
:

325 to 650mg per rectum every 4 to 6 hours whenever necessary
Do not exceed 4g/day

Indicated for Analgesia for Minor Joint/Muscle Pain:

Apply a thick layer of the cream or gel and massage it into the affected region.
Apply a patch to the affected area twice a day.

Indicated for Analgesia for Joint Pain or Minor Muscle
A transdermal patch (10% of methylsalicylate /3% of menthol): Apply one patch near the affected area, and leave it in place for nearly 8-12 hours; it should not exceed one patch for application if needed can; apply a 2nd patch for 8-12 hours, it should not exceed two patches for one/three days of use
A transdermal patch (10% of methylsalicylate /1.5% of menthol): Apply one patch near the affected area; it should not exceed three-four times a day, and leave in a place not more than 8 hours
Cream/ Balm/ foam /spray/ stick: Apply a small amount topically near the affected area and gently massage

Indicated for Fever and Analgesia
:

Immediate release
Regular strength: Administer 325 to 650 mg orally or rectally every 4 hours whenever needed
Do not exceed 3250mg/day
4g/day of daily dose can be used

Extra strength: Administer 1000mg orally three or four times a day whenever needed
Do not exceed 3000mg/day
4g/day of daily dose can be used

Extended-release
Administer two capsules (each capsule-650mg) thrice a day whenever needed
Do not exceed 3.9g/day

Maximum dose
Acetaminophen products-Do not exceed a total of 3.25g/day of acetaminophen
4g/day of daily dose can be used
Tylenol Extra Strength (Each tablet or capsule-500mg)-Do not exceed 3g/day
4g/day of daily dose can be used

Dose Adjustments

Hepatic impairment:
Do not exceed 3g/day,
Caution is needed

Renal impairment:
GFR≥50ml/min-Dosage adjustment is not needed
GFR 10 to 50ml/min-Administer for every 6 hours

GFR <10ml/min-Administer for every 8 hours
Renal replacement treatment- Administer every 6 hours

Indicated for the pain and cramps associated with menstruation
1 capsule orally every 4-6 hours as required

1 to 2 tablets or capsules orally every 4-6 times a day when necessary
Products differ; see the brand section and verify the specific labelling for each

obstetric :

50 to 100 mg Intramuscular or Subcutaneous injection, can be repeated every 1-3 hours as required. Maximum: 400 mg daily

Dose Adjustments

Dosing modifications:
Renal impairment
Mild-moderate: Dose reduction may be necessary.
Severe: use is Contraindicated
Hepatic impairment
Mild-moderate: Dose reduction may be necessary. Severe: use is Contraindicated

Indicated for menstrual cramps:

<12 years: Safety and efficacy not established
>12 years: 1-2 caplets orally every 4-6 hours whenever necessary. Do not exceed 8 caplets for 24 hours

Local Dermal Analgesia
Superficial dermatologic treatments
<3 years: Safety and Efficacy not established
>3 years: Patch- Before the treatment, apply the patch to healthy skin for 30 minutes

IV cannulation or Venipuncture
<3 years: Safety and Efficacy not established
>3 years: Patch- Before the treatment, apply the patch to healthy skin for 30 minutes

Indicated for Analgesia for Minor Muscle/Joint Pain:

<2 years: Safety and efficacy not established
>2 years: Apply a generous volume topically and massage the affected region three or four times daily

Indicated for analgesic/antipyretic:

>12 years: 325 to 650mg per rectum every 4 to 6 hours whenever necessary
6 to 12 years: 325 mg per rectum every 4 to 6 hours whenever necessary
3 to 6 years: 120 mg per rectum every 4 to 6 hours whenever necessary
1 to 3 years: 80 mg per rectum every 4 hours whenever necessary
3 months to 1 year: 80 mg per rectum every 6 hours whenever necessary

Maximum daily dose
≥12 years: Do not exceed 4g/day
<12 years: Do not exceed 5 doses for 24 hours

Indicated for Analgesia for Joint Pain or Minor Muscle
Age >12 years
A transdermal patch (10% of methylsalicylate /3% of menthol): Apply one patch near the affected area, and leave it in place for nearly 8-12 hours; it should not exceed one patch for application if needed can; apply a 2nd patch for 8-12 hours, it should not exceed two patches for one/three days of use
A transdermal patch (10% of methylsalicylate /1.5% of menthol): Apply one patch near the affected area; it should not exceed three-four times a day, and leave in a place not more than 8 hours
Cream/ Balm/ foam /spray/ stick: Apply a small amount topically near the affected area and gently massage
Age <12 years
Safety and efficacy not established

20-28 mg/kg/day orally divided every 6 hours
Administration
Take with 8-to-12-ounce water to ignore gastro-intestinal effects