Arthritis

Updated: July 12, 2024

Background

Epidemiology

Anatomy

Pathophysiology

Etiology

Genetics

Prognostic Factors

Clinical History

Physical Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

Medication

shark cartilage

Suggested Dosing
Ranging from 500 mg to 4.5 gm, taken orally in 2 to 6 divided doses daily

noni Juice

degenerative:

0.5 ounces (15ml) of noni juice 2 times a day

pau d’arco

1 to 4 g/day divided twice or thrice a day, should not use more than 7days
1 tsp of bark soaked in hot water 2–8 times per day.
Based on lapachol content, the recommended daily dose of lapachol is 1.5–2.0 g.

diclofenac topical

Voltaren Arthritis Pain gel
Avoid applying to more than two body regions at a time
Apply to affected areas four times daily
Dose for upper body region: around 2.25-inches for every upper body region
Dose for lower body region: around 4.5-inches for every lower body region

famprofazone

100 mg - 200 mg taken orally twice or thrice a day

taxifolin

(off-label):

taxifolin is currently being investigated for its potential health benefits, including antioxidant and anti-inflammatory properties. Research suggests it may have therapeutic potential in cardiovascular diseases, diabetes, neurodegenerative disorders, and cancer

serratiopeptidase

5 to 10mg given orally every 3 times a day, may increase to 10 to 30 mg daily

andrographolide

In vivo, data suggests the suggested dose is to take andrographolide 140 mg two times orally daily
The treatment duration is two years

artemotil

In vivo, data suggests the suggested dose is to take andrographolide 140 mg two times orally daily
The treatment duration is two years

sofnobrutinib

It is a selective and potent BTK inhibitor used orally
In a mice model of arthritis induced by collagen, it has shown anti-inflammatory properties

isoxicam

Isoxicam, a nonsteroidal anti-inflammatory agent, is predominantly utilized for treating conditions like rheumatoid arthritis and degenerative joint disease
The metabolism of [14C]-isoxicam was studied in normal, healthy adult male volunteers after the administration of a single daily oral dose of 300 mg

Dose Adjustments

Limited data is available

andiroba

It is applied directly in the affected area

Future Trends