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Croup

Updated : September 6, 2023





Background

The continuum of croup includes laryngotracheitis, laryngotracheobronchopneumonitis, and laryngotracheobronchitis.

Inspiratory stridor or a barking cough are symptoms of the frequent respiratory condition known as croup, which affects the bronchi, larynx, and trachea. Croup is normally brought on by parainfluenza infection, although it can also be brought on by a bacterium infection.

The diagnosis of croup is mostly clinical. First, it is necessary to rule out potentially fatal illnesses like epiglottitis and a foreign object in the airway. All croup patients should have corticosteroids, and those with mild to severe cases should only receive epinephrine.

Epidemiology

Croup causes 7 percent of hospitalizations for children under the age of 5 each year in the U. S. About 3 percent of kids to suffer from croup each year, usually between the ages of six months to three years old.

Approximately 75 percent of croup illnesses are caused by parainfluenza infection. With a ratio of 1.5:1, boys are more likely to have it than girls. Less than one percent of instances are deemed to be severe, while over 85 percent of cases are classified as mild croup.

Anatomy

Pathophysiology

WBC infiltration in the croup results in the enlargement of the trachea, larger bronchi, and larynx. Swelling causes a partial blockage of the airway, which, when severe, greatly increases the amount of labor required to breathe and produces the distinctively turbulent, bothersome airflow recognized as stridor.

Etiology

Most cases have a viral etiology, but some also have bacterial etiologies.

Bacterial

Laryngeal diphtheria, laryngotracheobronchopneumonitis, bacterial tracheitis, and laryngotracheobronchitis are the several types of bacterium croup.

Hemophilus influenza, Staphylococcus aureus, Moraxella catarrhalis, and Streptococcus pneumonia are the most typical bacterial culprits.

Corynebacterial diphtheria is the culprit behind larynx diphtheria. Bacterial infections that progress into laryngotracheobronchopneumonitis, tracheitis, and laryngotracheobronchitis generally start as viral illnesses.

Virus

Most frequently, types one and two of the parainfluenza viral produce acute laryngotracheitis or virus croup.

The viruses that cause acute laryngotracheitis and spasmodic croup both lack symptoms of illness.

Other causes include measles, adenovirus, RSV (respiratory syncytial virus), and influenzae A & B.

Genetics

Prognostic Factors

Clinical History

Physical Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

Medication

 
 

epinephrine racemic 

≥4 years: When required, provide 0.5 mL/kg of 2.25 percent solution using a jet nebulizer for 15 minutes for every 3 to 4 hours; the maximum dosage is 0.5 mL
<4 years: Whenever necessary, 0.05 mL of 2.25 percent solution in a jet nebulizer for 15 minutes, diluted to 3 mL with normal saline



 

Media Gallary

References

https://www.ncbi.nlm.nih.gov/books/NBK431070/

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Croup

Updated : September 6, 2023




The continuum of croup includes laryngotracheitis, laryngotracheobronchopneumonitis, and laryngotracheobronchitis.

Inspiratory stridor or a barking cough are symptoms of the frequent respiratory condition known as croup, which affects the bronchi, larynx, and trachea. Croup is normally brought on by parainfluenza infection, although it can also be brought on by a bacterium infection.

The diagnosis of croup is mostly clinical. First, it is necessary to rule out potentially fatal illnesses like epiglottitis and a foreign object in the airway. All croup patients should have corticosteroids, and those with mild to severe cases should only receive epinephrine.

Croup causes 7 percent of hospitalizations for children under the age of 5 each year in the U. S. About 3 percent of kids to suffer from croup each year, usually between the ages of six months to three years old.

Approximately 75 percent of croup illnesses are caused by parainfluenza infection. With a ratio of 1.5:1, boys are more likely to have it than girls. Less than one percent of instances are deemed to be severe, while over 85 percent of cases are classified as mild croup.

WBC infiltration in the croup results in the enlargement of the trachea, larger bronchi, and larynx. Swelling causes a partial blockage of the airway, which, when severe, greatly increases the amount of labor required to breathe and produces the distinctively turbulent, bothersome airflow recognized as stridor.

Most cases have a viral etiology, but some also have bacterial etiologies.

Bacterial

Laryngeal diphtheria, laryngotracheobronchopneumonitis, bacterial tracheitis, and laryngotracheobronchitis are the several types of bacterium croup.

Hemophilus influenza, Staphylococcus aureus, Moraxella catarrhalis, and Streptococcus pneumonia are the most typical bacterial culprits.

Corynebacterial diphtheria is the culprit behind larynx diphtheria. Bacterial infections that progress into laryngotracheobronchopneumonitis, tracheitis, and laryngotracheobronchitis generally start as viral illnesses.

Virus

Most frequently, types one and two of the parainfluenza viral produce acute laryngotracheitis or virus croup.

The viruses that cause acute laryngotracheitis and spasmodic croup both lack symptoms of illness.

Other causes include measles, adenovirus, RSV (respiratory syncytial virus), and influenzae A & B.

epinephrine racemic 

≥4 years: When required, provide 0.5 mL/kg of 2.25 percent solution using a jet nebulizer for 15 minutes for every 3 to 4 hours; the maximum dosage is 0.5 mL
<4 years: Whenever necessary, 0.05 mL of 2.25 percent solution in a jet nebulizer for 15 minutes, diluted to 3 mL with normal saline



https://www.ncbi.nlm.nih.gov/books/NBK431070/

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