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Cryopyrin Associated Periodic Syndromes

Updated : April 16, 2023



Background

Epidemiology

Anatomy

Pathophysiology

Etiology

Genetics

Prognostic Factors

Clinical History

Physical Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

Medication

 

rilonacept 

loading dose:

320

mg

Subcutaneous (SC)

Single dose


maintenance dose:160 mg subcutaneously administered once every week

note:
4.4 mg/kg subcutaneously administered once weekly
(not to exceed 320 mg)



canakinumab 

For individuals weighing over 40 kg, the recommended dosage is 150 mg administered subcutaneously every eight weeks
For individuals weighing between 15 to 40 kg, the initial dosage is 2 mg/kg of body weight, administered subcutaneously every eight weeks
The recommended dosage can be increased to 3 mg/kg If there is an inadequate response to the initial dose



 

rilonacept 

Age: 12-17 years
loading dose:

4.4

mg/kg

Subcutaneous (SC)


It is essential to ensure that the total dose does not exceed 320 mg

maintenance dose: 2.2 mg/kg via subcutaneous
do not exceed 160 mg or 2 mL per injection

Age: >18 years

loading dose: 320 mg subcutaneous once

maintenance dose: 160 mg subcutaneous injection once a week



canakinumab 

For Age ≥4 Years
For individuals weighing between 15-40 kg, administer 2 mg/kg subcutaneously every eight weeks
For individuals weighing 40 kg or more, administer 150 mg subcutaneously every eight weeks



 

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Cryopyrin Associated Periodic Syndromes

Updated : April 16, 2023


rilonacept 

loading dose:

320

mg

Subcutaneous (SC)

Single dose


maintenance dose:160 mg subcutaneously administered once every week

note:
4.4 mg/kg subcutaneously administered once weekly
(not to exceed 320 mg)



canakinumab 

For individuals weighing over 40 kg, the recommended dosage is 150 mg administered subcutaneously every eight weeks
For individuals weighing between 15 to 40 kg, the initial dosage is 2 mg/kg of body weight, administered subcutaneously every eight weeks
The recommended dosage can be increased to 3 mg/kg If there is an inadequate response to the initial dose



rilonacept 

Age: 12-17 years
loading dose:

4.4

mg/kg

Subcutaneous (SC)


It is essential to ensure that the total dose does not exceed 320 mg

maintenance dose: 2.2 mg/kg via subcutaneous
do not exceed 160 mg or 2 mL per injection

Age: >18 years

loading dose: 320 mg subcutaneous once

maintenance dose: 160 mg subcutaneous injection once a week



canakinumab 

For Age ≥4 Years
For individuals weighing between 15-40 kg, administer 2 mg/kg subcutaneously every eight weeks
For individuals weighing 40 kg or more, administer 150 mg subcutaneously every eight weeks



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Founded in 2014, medtigo is committed to providing high-quality, friendly physicians, transparent pricing, and a focus on building relationships and a lifestyle brand for medical professionals nationwide.

Facebook-f Twitter Instagram Youtube Linkedin Telegram

CONTACT INFORMATION

ADDRESS

MASSACHUSETTS – USA

60 Roberts Drive, Suite 313,
North Adams, MA 01247

MAHARASHTRA – INDIA

7, Shree Krishna, 2nd Floor,
Opp Kiosk Koffee,
Shirole Lane, Off FC Road,
Pune 411004, Maharashtra

 

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