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Diabetic Neuropathy

Updated : September 3, 2022





Background

Epidemiology

Anatomy

Pathophysiology

Etiology

Genetics

Prognostic Factors

Clinical History

Physical Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

Medication

 

tapentadol 

Indicated for diabetic peripheral neuropathy:

Immediate release:
Initial dose:50to 100mg orally every 4-6 hours
First dose: may be given as soon as 1 hour after the initial dose
The subsequent doses should be given every 4 to 6 hours, with the option to adjust the dosage to achieve adequate pain relief while still being tolerable to the patient. The available dosages are 50mg, 75mg, and 100mg

Acute moderate to severe pain
Immediate release solution: 50-100mg orally every 4-6 hours when necessary
Chronic: 50-250mg orally every 12 hours when necessary
Do not exceed 500mg/day

Opioid naïve patients:50mg orally every 12 hours when necessary. Do not exceed 500mg/day

Chronic severe pain
50-250mg orally every 12 hours when necessary
Do not exceed 500mg/day

Opioid naïve patients:50mg orally every 12 hours when necessary. Do not exceed 500mg/day



 
 

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References

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Diabetic Neuropathy

Updated : September 3, 2022




tapentadol 

Indicated for diabetic peripheral neuropathy:

Immediate release:
Initial dose:50to 100mg orally every 4-6 hours
First dose: may be given as soon as 1 hour after the initial dose
The subsequent doses should be given every 4 to 6 hours, with the option to adjust the dosage to achieve adequate pain relief while still being tolerable to the patient. The available dosages are 50mg, 75mg, and 100mg

Acute moderate to severe pain
Immediate release solution: 50-100mg orally every 4-6 hours when necessary
Chronic: 50-250mg orally every 12 hours when necessary
Do not exceed 500mg/day

Opioid naïve patients:50mg orally every 12 hours when necessary. Do not exceed 500mg/day

Chronic severe pain
50-250mg orally every 12 hours when necessary
Do not exceed 500mg/day

Opioid naïve patients:50mg orally every 12 hours when necessary. Do not exceed 500mg/day



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