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» Home » CAD » Nephrology » Acid-Base, Fluid, and Electrolyte Disorders » Metabolic Acidosis
Background
Epidemiology
Anatomy
Pathophysiology
Etiology
Genetics
Prognostic Factors
Clinical History
Physical Examination
Age group
Associated comorbidity
Associated activity
Acuity of presentation
Differential Diagnoses
Laboratory Studies
Imaging Studies
Procedures
Histologic Findings
Staging
Treatment Paradigm
by Stage
by Modality
Chemotherapy
Radiation Therapy
Surgical Interventions
Hormone Therapy
Immunotherapy
Hyperthermia
Photodynamic Therapy
Stem Cell Transplant
Targeted Therapy
Palliative Care
Medication
Indicated for Alkalinizing Agent
Depending upon the severity of the metabolic acidosis, the dosage is directed by a physician
Not posing a threat to life: Intravenous infusion of 2 to 5 milliequivalents/kg over a period of 4 to 8 hours based on the severity of acidosis as determined by the decrease in total CO2 content, clinical state and pH.
Severe (except hyper carbic acidosis): 90 to 180 milliequivalents/liter at a pace of 1 to 1.5 liters during the first hour and adjust for subsequent treatment as required
Dosing Considerations
Observe serum potassium, carbon di oxide and pH
veverimer(Pending FDA approval)
Metabolic acidosis in individuals with chronic renal disease: Pending FDA clearance
Indicated for Alkalinizing Agent
Depending upon the severity of the metabolic acidosis, the dosage is directed by a physician
For older children: Administer an intravenous infusion of 2 to 5 milliequivalent/kg over a period of 4 to 8 hours, depending on the extent of acidosis as determined by the decrease in total CO2 content, clinical condition and pH level
In cases of acidosis with a pH level below 7.0 to 7.2, an intravenous infusion of 0.25 to 2 milliequivalent/kg can be considered
Dosing Considerations
Observe the serum potassium
Future Trends
References
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» Home » CAD » Nephrology » Acid-Base, Fluid, and Electrolyte Disorders » Metabolic Acidosis
Indicated for Alkalinizing Agent
Depending upon the severity of the metabolic acidosis, the dosage is directed by a physician
Not posing a threat to life: Intravenous infusion of 2 to 5 milliequivalents/kg over a period of 4 to 8 hours based on the severity of acidosis as determined by the decrease in total CO2 content, clinical state and pH.
Severe (except hyper carbic acidosis): 90 to 180 milliequivalents/liter at a pace of 1 to 1.5 liters during the first hour and adjust for subsequent treatment as required
Dosing Considerations
Observe serum potassium, carbon di oxide and pH
veverimer(Pending FDA approval)
Metabolic acidosis in individuals with chronic renal disease: Pending FDA clearance
Indicated for Alkalinizing Agent
Depending upon the severity of the metabolic acidosis, the dosage is directed by a physician
For older children: Administer an intravenous infusion of 2 to 5 milliequivalent/kg over a period of 4 to 8 hours, depending on the extent of acidosis as determined by the decrease in total CO2 content, clinical condition and pH level
In cases of acidosis with a pH level below 7.0 to 7.2, an intravenous infusion of 0.25 to 2 milliequivalent/kg can be considered
Dosing Considerations
Observe the serum potassium
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