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Metabolic Alkalosis

Updated : December 14, 2022





Background

Epidemiology

Anatomy

Pathophysiology

Etiology

Genetics

Prognostic Factors

Clinical History

Physical Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

Medication

 

ammonium chloride 

Indicated for Metabolic Alkalosis and Hypochloremic States:


mEq of chloride ion (NH4Cl) = [0.2 L/kg X Body weight(kg)] X [103 - measured serum chloride]; provide 50% of the dosage over 12 hours and reassess.
The typical range for serum chloride concentration is 103 mEq/L, while the distribution volume for chloride is 0.2 L/kg.



lysine 

10 g orally everyday divided doses of upto 5 days



Dose Adjustments

Dosing modifications
Kidney Impairment
dosage adjustment is not necessary
Hepatic Impairment
dosage adjustment is not necessary

 

ammonium chloride 

Indicated for Metabolic Alkalosis and Hypochloremic States:


mEq of chloride ion (NH4Cl) = [0.2 L/kg X Bodyweight (kg)] X [103 - measured serum chloride]; provide 50% of the dosage over 12 hours and reassess.
The typical range for serum chloride concentration is 103 mEq/L, while the distribution volume for chloride is 0.2 L/kg.



 

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References

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Metabolic Alkalosis

Updated : December 14, 2022




ammonium chloride 

Indicated for Metabolic Alkalosis and Hypochloremic States:


mEq of chloride ion (NH4Cl) = [0.2 L/kg X Body weight(kg)] X [103 - measured serum chloride]; provide 50% of the dosage over 12 hours and reassess.
The typical range for serum chloride concentration is 103 mEq/L, while the distribution volume for chloride is 0.2 L/kg.



lysine 

10 g orally everyday divided doses of upto 5 days



Dose Adjustments

Dosing modifications
Kidney Impairment
dosage adjustment is not necessary
Hepatic Impairment
dosage adjustment is not necessary

ammonium chloride 

Indicated for Metabolic Alkalosis and Hypochloremic States:


mEq of chloride ion (NH4Cl) = [0.2 L/kg X Bodyweight (kg)] X [103 - measured serum chloride]; provide 50% of the dosage over 12 hours and reassess.
The typical range for serum chloride concentration is 103 mEq/L, while the distribution volume for chloride is 0.2 L/kg.



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