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paraphilia

Updated : September 6, 2023





Background

Paraphilias are sexual cravings, fantasies, or behaviors that are persistent and recurrent and include unusual objects, activities, or even circumstances. A paraphilic condition can develop even though paraphilia is not inherently pathological if it causes suffering, distress, and functional disability in the lives of the affected person or any others.

The DSM V classifies exhibitionism, sexual masochism, pedophilia, sexual sadism, fetishism, frotteurism, transvestic fetishism, and voyeurism as eight separate paraphilias. Any sexual interaction with a prepubescent kid in which the perpetrator/patient is at a minimum of 16 years old, as well as the victim is at least 5 years smaller, is considered to be pedophilic.

The act of exposing one’s genitalia to unaware outsiders for sexual gratification is known as exhibitionism. Voyeurism is the act of seeing a stranger engage in sexual or intimate behavior. When a nonconsenting individual is subjected to physical or mental suffering in order to arouse oneself sexually, this is known as sexual sadism.

The source of sexual arousal in sexual masochism is suffering from physical, emotional, and/or social abuse and humiliation. The act of rubbing or touching against a nonconsenting individual is known as Frotteurism. Fetishism is the practice of using non-living objects—typically shoes and underwear—for sexual gratification. Cross-dressing or appearing in the opposite gender is the source of sexual excitement in transvestic fetishism.

Epidemiology

Information on the epidemiology of paraphilia and paraphilic conditions is scarce in the literature. From an epidemiological perspective, there is a dearth of literature because paraphilia is often examined in a broad sense rather than in relation to particular paraphilias or paraphilic conditions. For unexplained reasons, men tend to have paraphilias more frequently than women.

In the latest report, the urge for or awareness of paraphilic activities was particularly examined in a population sample that was demographically representative of the overall population. A total of 1,040 people from various demographic groups—including ethnicity, gender, religion, age, education, and place of residence—made up the size of the sample.

Nearly half of the survey group indicated an interest in one or even more paraphilic classes, with around a third of this cohort actually acting on this desire at least once, according to the researchers. A frequency of 15.9 percent was found for fetishism, masochism, frotteurism, and voyeurism with involvement in both females and males (a value rated statistically exceptional).

There was no statistically meaningful difference between females and males in terms of interest in masochism and fetishism. The study discovered that fetishism and voyeurism are frequently the most prevalent paraphilic interests among men.

Anatomy

Pathophysiology

Etiology

It is unclear what causes paraphilia and related conditions. But it’s believed that a mix of neurological, cognitive, and interpersonal functions are all involved. Numerous genetic variables have been implicated in the development of pedophilia and pedophilic condition, and new research has shown a strong link between paraphilic children child abusers and the COMT Val158Met (rs4680) polymorphisms.

The pathophysiology of paraphilic illnesses and the general disruption of the conscious management of behavior have both been shown to be significantly influenced by central dopamine, according to a new study on the neuronal activity of paraphilic diseases.

According to the study’s findings, the test population with paraphilic illnesses had lower levels of DOPAC (3,4-dihydroxyphenylacetic acid) and higher amounts of norepinephrine and serotonin in their urine samples. Norepinephrine and serotonin have been linked to compulsive disorders, and DOPAC has been linked to affective and dissociative abnormalities, according to research.

Genetics

Prognostic Factors

A definitive cure or transformation has not yet been proven, despite the pharmaceutical and psychological interventions created to manage paraphilia and paraphilic illnesses. Existing methods just allow for improved voluntary management over sexual arousal and a decrease in sexual drive, with the best results only coming from people who are truly willing to change.

The intensity and regularity of deviant sexual desire and the accompanying behaviors are significantly reduced in those who do participate in therapy, either alone or, preferably, in conjunction with medical care. However, research indicates that the majority of sexual criminals are likely to commit crimes again.

Clinical History

Physical Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

Medication

 

cyproterone

50 - 200

mg

Orally 

once a day

(do not exceed 600 mg/day)
or
300 to 600 mg IM every 1 to 2 weeks or
400 to 700 mg IM once a week
Do not use if hepatic failure, thromboembolic disease, or active pituitary pathology.



 
 

Media Gallary

References

https://www.ncbi.nlm.nih.gov/books/NBK554425/

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paraphilia

Updated : September 6, 2023




Paraphilias are sexual cravings, fantasies, or behaviors that are persistent and recurrent and include unusual objects, activities, or even circumstances. A paraphilic condition can develop even though paraphilia is not inherently pathological if it causes suffering, distress, and functional disability in the lives of the affected person or any others.

The DSM V classifies exhibitionism, sexual masochism, pedophilia, sexual sadism, fetishism, frotteurism, transvestic fetishism, and voyeurism as eight separate paraphilias. Any sexual interaction with a prepubescent kid in which the perpetrator/patient is at a minimum of 16 years old, as well as the victim is at least 5 years smaller, is considered to be pedophilic.

The act of exposing one’s genitalia to unaware outsiders for sexual gratification is known as exhibitionism. Voyeurism is the act of seeing a stranger engage in sexual or intimate behavior. When a nonconsenting individual is subjected to physical or mental suffering in order to arouse oneself sexually, this is known as sexual sadism.

The source of sexual arousal in sexual masochism is suffering from physical, emotional, and/or social abuse and humiliation. The act of rubbing or touching against a nonconsenting individual is known as Frotteurism. Fetishism is the practice of using non-living objects—typically shoes and underwear—for sexual gratification. Cross-dressing or appearing in the opposite gender is the source of sexual excitement in transvestic fetishism.

Information on the epidemiology of paraphilia and paraphilic conditions is scarce in the literature. From an epidemiological perspective, there is a dearth of literature because paraphilia is often examined in a broad sense rather than in relation to particular paraphilias or paraphilic conditions. For unexplained reasons, men tend to have paraphilias more frequently than women.

In the latest report, the urge for or awareness of paraphilic activities was particularly examined in a population sample that was demographically representative of the overall population. A total of 1,040 people from various demographic groups—including ethnicity, gender, religion, age, education, and place of residence—made up the size of the sample.

Nearly half of the survey group indicated an interest in one or even more paraphilic classes, with around a third of this cohort actually acting on this desire at least once, according to the researchers. A frequency of 15.9 percent was found for fetishism, masochism, frotteurism, and voyeurism with involvement in both females and males (a value rated statistically exceptional).

There was no statistically meaningful difference between females and males in terms of interest in masochism and fetishism. The study discovered that fetishism and voyeurism are frequently the most prevalent paraphilic interests among men.

It is unclear what causes paraphilia and related conditions. But it’s believed that a mix of neurological, cognitive, and interpersonal functions are all involved. Numerous genetic variables have been implicated in the development of pedophilia and pedophilic condition, and new research has shown a strong link between paraphilic children child abusers and the COMT Val158Met (rs4680) polymorphisms.

The pathophysiology of paraphilic illnesses and the general disruption of the conscious management of behavior have both been shown to be significantly influenced by central dopamine, according to a new study on the neuronal activity of paraphilic diseases.

According to the study’s findings, the test population with paraphilic illnesses had lower levels of DOPAC (3,4-dihydroxyphenylacetic acid) and higher amounts of norepinephrine and serotonin in their urine samples. Norepinephrine and serotonin have been linked to compulsive disorders, and DOPAC has been linked to affective and dissociative abnormalities, according to research.

A definitive cure or transformation has not yet been proven, despite the pharmaceutical and psychological interventions created to manage paraphilia and paraphilic illnesses. Existing methods just allow for improved voluntary management over sexual arousal and a decrease in sexual drive, with the best results only coming from people who are truly willing to change.

The intensity and regularity of deviant sexual desire and the accompanying behaviors are significantly reduced in those who do participate in therapy, either alone or, preferably, in conjunction with medical care. However, research indicates that the majority of sexual criminals are likely to commit crimes again.

cyproterone

50 - 200

mg

Orally 

once a day

(do not exceed 600 mg/day)
or
300 to 600 mg IM every 1 to 2 weeks or
400 to 700 mg IM once a week
Do not use if hepatic failure, thromboembolic disease, or active pituitary pathology.



https://www.ncbi.nlm.nih.gov/books/NBK554425/

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