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» Home » CAD » Cardiology » Coronary artery disease » Percutaneous intervention (PCI)
Background
Epidemiology
Anatomy
Pathophysiology
Etiology
Genetics
Prognostic Factors
Clinical History
Physical Examination
Age group
Associated comorbidity
Associated activity
Acuity of presentation
Differential Diagnoses
Laboratory Studies
Imaging Studies
Procedures
Histologic Findings
Staging
Treatment Paradigm
by Stage
by Modality
Chemotherapy
Radiation Therapy
Surgical Interventions
Hormone Therapy
Immunotherapy
Hyperthermia
Photodynamic Therapy
Stem Cell Transplant
Targeted Therapy
Palliative Care
Medication
Indicated for Percutaneous Coronary Intervention:
0.75mg/kg Intravenous bolus, followed by 1.75 mg/kg/hr intravenous infusion throughout the procedure
Obtain the activated coagulation time (ACT) 5 minutes after administering the bolus dose; if necessary, administer an additional intravenous bolus of 0.3 mg/kg
Consider an extended infusion duration of 1.75 mg/kg/hr for up to 4 hours following PCI in patients with ST-segment elevation MI. (STEMI)
Dose Adjustments
Hepatic Impairment
No Dose Modification Is Necessary
Renal Impairment
Bolus dose:
No dosage adjustment is necessary
Intravenous infusion:
Moderate (CrCl 30-59 mL/min): 1.75 mg/kg/hr
Hemodialysis: 0.25 mg/kg/hr
Severe (CrCl <30 mL/min): 1 mg/kg/hr
Future Trends
References
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» Home » CAD » Cardiology » Coronary artery disease » Percutaneous intervention (PCI)
Indicated for Percutaneous Coronary Intervention:
0.75mg/kg Intravenous bolus, followed by 1.75 mg/kg/hr intravenous infusion throughout the procedure
Obtain the activated coagulation time (ACT) 5 minutes after administering the bolus dose; if necessary, administer an additional intravenous bolus of 0.3 mg/kg
Consider an extended infusion duration of 1.75 mg/kg/hr for up to 4 hours following PCI in patients with ST-segment elevation MI. (STEMI)
Dose Adjustments
Hepatic Impairment
No Dose Modification Is Necessary
Renal Impairment
Bolus dose:
No dosage adjustment is necessary
Intravenous infusion:
Moderate (CrCl 30-59 mL/min): 1.75 mg/kg/hr
Hemodialysis: 0.25 mg/kg/hr
Severe (CrCl <30 mL/min): 1 mg/kg/hr
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