- July 21, 2022
- Newsletter
- 617-430-5616
Menu
Menu
Menu
Menu
Menu
Menu
ADVERTISEMENT
ADVERTISEMENT
Background
Epidemiology
Anatomy
Pathophysiology
Etiology
Genetics
Prognostic Factors
Clinical History
Physical Examination
Age group
Associated comorbidity
Associated activity
Acuity of presentation
Differential Diagnoses
Laboratory Studies
Imaging Studies
Procedures
Histologic Findings
Staging
Treatment Paradigm
by Stage
by Modality
Chemotherapy
Radiation Therapy
Surgical Interventions
Hormone Therapy
Immunotherapy
Hyperthermia
Photodynamic Therapy
Stem Cell Transplant
Targeted Therapy
Palliative Care
Medication
1 g IM or IV given every 12hrs for mild conditions
1-2 g IM or IV every 8hrs moderate to severe infections
2 g IV every 6-8hrs high dosing for infections
2 g IV every 4hrs for life-threatening infections
12 g is the maximum dose required per day
1-2 g IV or IM every 12hrs for moderate infections
2 g IV every 12hrs for Severe infections
3 g IV every 12hrs for Life-threatening infections
The maximum duration of therapy is seven days
Loading Dose: 200 mg via IV infusion for 1 hour on day 1 or 100 mg via IV infusion for 30mins two times on day 1 or 300 mg orally two times on day 1
Maintenance Dose: 100 mg via IV infusion for 30mins per day or 300 mg orally per day
the maximum duration of treatment is 7-14 days
500
mg
Tablet
Orally
every 8 hrs
5
days
Extend the therapy duration as per vital signs
1-2 g IV or IM was given once a day or in equally divided doses 2x a day
maximum duration of therapy is 4-14 days
prolonged treatment recommends for complicated infections
At least treatment given ten days for diseases due to streptococcus
800
mg
Orally
once a day
7 - 10
days
500
mg
2 times a day or 1 g daily
10
days
ER: 775 mg daily for 10 days
1.2 million units given IM daily as a single dose
400
mg
Orally
divided in to 2 times a day
10
days
Indicated for Streptococcal pharyngitis:
250 mg oral tablet immediate release twice a day for 14 days
500 mg oral tablet immediate release twice a day for a minimum of 5 days
250
mg
Capsule
Orally
every 6 hrs
1
g
orally
daily
10
days
Note: indicated for pharyngitis and tonsillitis caused by Group A beta-hemolytic streptococci
500 mg orally once a day, followed by 250 mg 4 times a day, on the 2nd to 5th day.
125 - 250
mg
Orally
every 8 hrs
10
days
1-2g intramuscular or intravenous every 8 to 12 hours
Do not exceed 8g/day
Take 400 mg orally after every 12 hours up to 14 days.
Take 200 mg orally after every 12 hours up to 10 days
Renal Impairment
For creatinine clearance of 30 to 49 ml/minute/1.73 square meter: maximum up to 200 mg orally after every 12 hours
For creatinine clearance of <30 ml/minute/1.73/square meter: every day 200 mg orally
End-stage: dose not determined yet
Pending for FDA approval
1 to 2 grams intravenous/intramuscular given every 2 times a day
300 mg in single dose or two divided doses every day
Administer dose of 500 mg intramuscularly or intravenously every 6 hours
Children and Adolescents: :
50 mg/kg/day orally daily or in divided doses 2 times a day for 10 days; may be increase up to 1,000 mg/day
ER: 775 mg orally daily for 10 days
Age > 12 years:
125 - 250
mg
Orally
every 6-8 hrs
10
days
wt <27 kg: 600,000 U IM daily
wt > 27 kg: 1.2 million U IM daily
30
mg/kg
orally
daily
Indicated for Streptococcal Pharyngitis:
20-30 mg/kg/day orally divided 3 times for Chronic carrier treatment
7 mg/kg/dose 3 times daily for 10 days for Acute treatment
25 - 50
mg/kg
Capsule
Orally
every 8 hrs
10
days
≤7 days:
<2kg bodyweight: 30mg/kg intravenous every 12 hours
>2 kg bodyweight: 30mg/kg intravenous every 8 hours
8 to 30 days:
<1.2kg: 30mg/kg intravenous every 12 hours
1.2kg-2kg: 30mg/kg intravenous every 8 hours
>2kg: 30mg/kg intravenous every 6 hours
1 to 18 years: 30mg/kg intravenous every 6-8 hours
Children >8 years and adolescents:
1 to 2 mg/kg per dose twice a day for 10 days
Pending for FDA approval
Children up to 12 years: 5 to 8 mg/kg in two divided doses every day; maximum dose: 150 mg 2 times a day
for infants and Children:
Administer daily dose of 50 to 100 mg/kg intramuscularly or intravenously divided doses every 4 to 8 hours
Future Trends
References
ADVERTISEMENT
1 g IM or IV given every 12hrs for mild conditions
1-2 g IM or IV every 8hrs moderate to severe infections
2 g IV every 6-8hrs high dosing for infections
2 g IV every 4hrs for life-threatening infections
12 g is the maximum dose required per day
1-2 g IV or IM every 12hrs for moderate infections
2 g IV every 12hrs for Severe infections
3 g IV every 12hrs for Life-threatening infections
The maximum duration of therapy is seven days
Loading Dose: 200 mg via IV infusion for 1 hour on day 1 or 100 mg via IV infusion for 30mins two times on day 1 or 300 mg orally two times on day 1
Maintenance Dose: 100 mg via IV infusion for 30mins per day or 300 mg orally per day
the maximum duration of treatment is 7-14 days
500
mg
Tablet
Orally
every 8 hrs
5
days
Extend the therapy duration as per vital signs
1-2 g IV or IM was given once a day or in equally divided doses 2x a day
maximum duration of therapy is 4-14 days
prolonged treatment recommends for complicated infections
At least treatment given ten days for diseases due to streptococcus
800
mg
Orally
once a day
7 - 10
days
500
mg
2 times a day or 1 g daily
10
days
ER: 775 mg daily for 10 days
1.2 million units given IM daily as a single dose
400
mg
Orally
divided in to 2 times a day
10
days
Indicated for Streptococcal pharyngitis:
250 mg oral tablet immediate release twice a day for 14 days
500 mg oral tablet immediate release twice a day for a minimum of 5 days
250
mg
Capsule
Orally
every 6 hrs
1
g
orally
daily
10
days
Note: indicated for pharyngitis and tonsillitis caused by Group A beta-hemolytic streptococci
500 mg orally once a day, followed by 250 mg 4 times a day, on the 2nd to 5th day.
125 - 250
mg
Orally
every 8 hrs
10
days
1-2g intramuscular or intravenous every 8 to 12 hours
Do not exceed 8g/day
Take 400 mg orally after every 12 hours up to 14 days.
Take 200 mg orally after every 12 hours up to 10 days
Renal Impairment
For creatinine clearance of 30 to 49 ml/minute/1.73 square meter: maximum up to 200 mg orally after every 12 hours
For creatinine clearance of <30 ml/minute/1.73/square meter: every day 200 mg orally
End-stage: dose not determined yet
Pending for FDA approval
1 to 2 grams intravenous/intramuscular given every 2 times a day
300 mg in single dose or two divided doses every day
Administer dose of 500 mg intramuscularly or intravenously every 6 hours
Children and Adolescents: :
50 mg/kg/day orally daily or in divided doses 2 times a day for 10 days; may be increase up to 1,000 mg/day
ER: 775 mg orally daily for 10 days
Age > 12 years:
125 - 250
mg
Orally
every 6-8 hrs
10
days
wt <27 kg: 600,000 U IM daily
wt > 27 kg: 1.2 million U IM daily
30
mg/kg
orally
daily
Indicated for Streptococcal Pharyngitis:
20-30 mg/kg/day orally divided 3 times for Chronic carrier treatment
7 mg/kg/dose 3 times daily for 10 days for Acute treatment
25 - 50
mg/kg
Capsule
Orally
every 8 hrs
10
days
≤7 days:
<2kg bodyweight: 30mg/kg intravenous every 12 hours
>2 kg bodyweight: 30mg/kg intravenous every 8 hours
8 to 30 days:
<1.2kg: 30mg/kg intravenous every 12 hours
1.2kg-2kg: 30mg/kg intravenous every 8 hours
>2kg: 30mg/kg intravenous every 6 hours
1 to 18 years: 30mg/kg intravenous every 6-8 hours
Children >8 years and adolescents:
1 to 2 mg/kg per dose twice a day for 10 days
Pending for FDA approval
Children up to 12 years: 5 to 8 mg/kg in two divided doses every day; maximum dose: 150 mg 2 times a day
for infants and Children:
Administer daily dose of 50 to 100 mg/kg intramuscularly or intravenously divided doses every 4 to 8 hours
Pending for FDA approval
Founded in 2014, medtigo is committed to providing high-quality, friendly physicians, transparent pricing, and a focus on building relationships and a lifestyle brand for medical professionals nationwide.
USA – BOSTON
60 Roberts Drive, Suite 313
North Adams, MA 01247
INDIA – PUNE
7, Shree Krishna, 2nd Floor, Opp Kiosk Koffee, Shirole Lane, Off FC Road, Pune 411004, Maharashtra
Founded in 2014, medtigo is committed to providing high-quality, friendly physicians, transparent pricing, and a focus on building relationships and a lifestyle brand for medical professionals nationwide.
MASSACHUSETTS – USA
60 Roberts Drive, Suite 313,
North Adams, MA 01247
MAHARASHTRA – INDIA
7, Shree Krishna, 2nd Floor,
Opp Kiosk Koffee,
Shirole Lane, Off FC Road,
Pune 411004, Maharashtra
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
