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Small Cell Carcinoma

Updated : April 26, 2022



Background

Epidemiology

Anatomy

Pathophysiology

Etiology

Genetics

Prognostic Factors

Clinical History

Physical Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

Medication

 

durvalumab

1500

mg

Intravenous (IV)

every 4 weeks

for 4 cycles in combination with etoposide and carboplatin/cisplatin



 

durvalumab

Initial dose:

20

mg/kg

Intravenous (IV)

every 3 weeks

for 4 cycles in combination with etoposide and carboplatin or cisplatin



durvalumab

Maintenance dose:

10

mg

Intravenous (IV)

every 2 weeks

or continue until disease progression or severe health side effects



Dose Adjustments

Dose adjustment for hepatic impairment: Terminate the therapy temporarily if AST or ALT >3 up to 8 × ULN or total bilirubin >1.5 up to 3 × ULN Discontinue the treatment permanently if AST or ALT >8 × ULN or total bilirubin >3 × ULN

 

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Small Cell Carcinoma

Updated : April 26, 2022


durvalumab

1500

mg

Intravenous (IV)

every 4 weeks

for 4 cycles in combination with etoposide and carboplatin/cisplatin



durvalumab

Initial dose:

20

mg/kg

Intravenous (IV)

every 3 weeks

for 4 cycles in combination with etoposide and carboplatin or cisplatin



durvalumab

Maintenance dose:

10

mg

Intravenous (IV)

every 2 weeks

or continue until disease progression or severe health side effects



Dose Adjustments

Dose adjustment for hepatic impairment: Terminate the therapy temporarily if AST or ALT >3 up to 8 × ULN or total bilirubin >1.5 up to 3 × ULN Discontinue the treatment permanently if AST or ALT >8 × ULN or total bilirubin >3 × ULN

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Founded in 2014, medtigo is committed to providing high-quality, friendly physicians, transparent pricing, and a focus on building relationships and a lifestyle brand for medical professionals nationwide.

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CONTACT INFORMATION

ADDRESS

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60 Roberts Drive, Suite 313,
North Adams, MA 01247

MAHARASHTRA – INDIA

7, Shree Krishna, 2nd Floor,
Opp Kiosk Koffee,
Shirole Lane, Off FC Road,
Pune 411004, Maharashtra

 

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