Subarachnoid Block

Updated: June 26, 2024

Background

Epidemiology

Anatomy

Pathophysiology

Etiology

Genetics

Prognostic Factors

Clinical History

Physical Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

Medication

bupivacaine

vaginal hysterectomy:

7.5 mg or 1

appendectomy :12 mg or 1.6 mL

chloroprocaine

Indicated for Subarachnoid Block
For intrathecal use: 50 mg is the recommended dose to obtain effective block to T-10 level with one single administration in an average adult of nearly 70 kg
Safety and efficacy not established for dose > 50 mg
Central Nerve Block
2% & 3% injections of Nesacaine-MPF in single-dose vial lack of preservative
Lumbar epidural block, 2-3% solutions: 2 ml-2.5 ml per segment, 15-25 ml as the total volume; 2 ml-6 ml as repeat doses less than original dose might be given at 40-50 minutes intervals
Caudal block, 2%, and 3% solution: 15 ml-25 ml as initial dose; repeat doses might be given at 40-60 minutes intervals
Infiltration and Peripheral Nerve Block
Nesacaine/Nesacaine-MPF 1% and 2% as total doses:
2% solution (Pudendal): 400 mg of chloroprocaine (10 ml on each side)
2% solution (Brachial plexus): 600 mg-800 mg of chloroprocaine (30 ml-40 mL)
2% solution (Infraorbital): 10 mg-20 mg of chloroprocaine (0.5 ml-1 ml)
2% solution (Mandibular): 40 mg-60 mg of chloroprocaine (2 ml-3 mL)
1% solution (Digital, without epinephrine): 30 mg-40 mg of chloroprocaine (3 ml-4 ml)
1% solution (Paracervical): Nearly 120 mg of chloroprocaine (3 ml per each side of 4 sites)
It should not exceed 800 mg as a single dose
It should not exceed 1000 mg as a single dose with epinephrine
Cervical region /thoracic region: 30 mg-60 mg of chloroprocaine per each segment, which is to be anesthetized
2% injection of Nesacaine-MPF in a single-dose vial lacking preservative used for local anesthesia
2% & 3% injections of Nesacaine in multi-dose vial with the preservative used for local anesthesia