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» Home » CAD » Anesthesia and Perioperative Care » Perioperative and Intraoperative Events » Procedural Sedation
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» Home » CAD » Anesthesia and Perioperative Care » Perioperative and Intraoperative Events » Procedural Sedation
Background
Epidemiology
Anatomy
Pathophysiology
Etiology
Genetics
Prognostic Factors
Clinical History
Physical Examination
Age group
Associated comorbidity
Associated activity
Acuity of presentation
Differential Diagnoses
Laboratory Studies
Imaging Studies
Procedures
Histologic Findings
Staging
Treatment Paradigm
by Stage
by Modality
Chemotherapy
Radiation Therapy
Surgical Interventions
Hormone Therapy
Immunotherapy
Hyperthermia
Photodynamic Therapy
Stem Cell Transplant
Targeted Therapy
Palliative Care
Medication
Induction:
5 mg IV over 60 seconds
Patients with ASA-PS III/IV: 2.5-5 mg IV push over 1 minute, depending on patient condition.
Maintenance:
2.5 mg IV infusion administered over 15 seconds
1.25-2.5 mg IV push over 15 seconds for ASA-PS III/IV patients; at least 2 minutes must elapse before administering any supplemental dose.
Indicated for Pre-procedure Sedation :
200 - 300
mg
orally
Prior to surgery
Dose Adjustments
Renal Impairment
lower dose recommended
Hepatic Impairment
lower dose recommended
0.1mg/kg intravenous bolus for 1-3 doses
400mg orally before the surgery
Loading dose: 1 mcg/kg Intravenous over 10 mins
Maintenance dose: 0.6 mcg/kg/hr Intravenous titrate to effect (generally 0.2 to 1 mcg/kg/hr)
fiberoptic intubation while Awake
Loading dose: 1 mcg/kg Intravenous over 10 mins
Maintenance dose: 0.7 mcg/kg/hr Intravenous till endotracheal tube is secured
0.1-0.4 mg/kg intravenous bolus once
200mg orally before the surgery
Before the procedure, administer 1 to 3 mg/kg Intramuscularly, intravenously, or orally for 1 to 1.5 hours
2mg/kg orally thrice a day
2 to 6 mg/kg Intramuscular, OR
1 to 3 mg/kg Intravenous
Should not exceed more than 100 mg
Less than 1 month: Safety & efficacy were not established
Sedation is initiated during non-invasive procedures
1 month to less than 2 yrs: 1.5 mcg/kg intravenous loading infusion; infuse for 10 minutes
2 yrs to less than 18 yrs: 2 mcg/kg intravenous loading infusion; infuse for 10 minutes
if clinically indicated, Consider lowering dose
Sedation should be maintained throughout non-invasive procedures
1 month to less than 18 yrs: 1.5 mcg/kg/hr intravenous initially; titrate inorder to achieve a desired clinical effect within a dose range of about 0.5 to 1.5 mcg/kg/hr
Take a dose of 50 to 75 mg/kg orally, 30 to 60 min prior to procedure and this may be repeated in half an hour, if required
Dose should not be more than 1 g in infants and 2 g in children
20 - 50
mcg/kg
Solution
Intramuscular (IM)
Loading dose: 1 mcg/kg Intravenous over 10 mins
Maintenance dose: 0.6 mcg/kg/hr Intravenous titrate to effect (generally 0.2 to 1 mcg/kg/hr)
fiberoptic intubation while Awake
Loading dose: 1 mcg/kg Intravenous over 10 mins
Maintenance dose: 0.7 mcg/kg/hr Intravenous till endotracheal tube is secured
Future Trends
References
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» Home » CAD » Anesthesia and Perioperative Care » Perioperative and Intraoperative Events » Procedural Sedation
Induction:
5 mg IV over 60 seconds
Patients with ASA-PS III/IV: 2.5-5 mg IV push over 1 minute, depending on patient condition.
Maintenance:
2.5 mg IV infusion administered over 15 seconds
1.25-2.5 mg IV push over 15 seconds for ASA-PS III/IV patients; at least 2 minutes must elapse before administering any supplemental dose.
Indicated for Pre-procedure Sedation :
200 - 300
mg
orally
Prior to surgery
Dose Adjustments
Renal Impairment
lower dose recommended
Hepatic Impairment
lower dose recommended
0.1mg/kg intravenous bolus for 1-3 doses
400mg orally before the surgery
Loading dose: 1 mcg/kg Intravenous over 10 mins
Maintenance dose: 0.6 mcg/kg/hr Intravenous titrate to effect (generally 0.2 to 1 mcg/kg/hr)
fiberoptic intubation while Awake
Loading dose: 1 mcg/kg Intravenous over 10 mins
Maintenance dose: 0.7 mcg/kg/hr Intravenous till endotracheal tube is secured
0.1-0.4 mg/kg intravenous bolus once
200mg orally before the surgery
Before the procedure, administer 1 to 3 mg/kg Intramuscularly, intravenously, or orally for 1 to 1.5 hours
2mg/kg orally thrice a day
2 to 6 mg/kg Intramuscular, OR
1 to 3 mg/kg Intravenous
Should not exceed more than 100 mg
Less than 1 month: Safety & efficacy were not established
Sedation is initiated during non-invasive procedures
1 month to less than 2 yrs: 1.5 mcg/kg intravenous loading infusion; infuse for 10 minutes
2 yrs to less than 18 yrs: 2 mcg/kg intravenous loading infusion; infuse for 10 minutes
if clinically indicated, Consider lowering dose
Sedation should be maintained throughout non-invasive procedures
1 month to less than 18 yrs: 1.5 mcg/kg/hr intravenous initially; titrate inorder to achieve a desired clinical effect within a dose range of about 0.5 to 1.5 mcg/kg/hr
Take a dose of 50 to 75 mg/kg orally, 30 to 60 min prior to procedure and this may be repeated in half an hour, if required
Dose should not be more than 1 g in infants and 2 g in children
20 - 50
mcg/kg
Solution
Intramuscular (IM)
Loading dose: 1 mcg/kg Intravenous over 10 mins
Maintenance dose: 0.6 mcg/kg/hr Intravenous titrate to effect (generally 0.2 to 1 mcg/kg/hr)
fiberoptic intubation while Awake
Loading dose: 1 mcg/kg Intravenous over 10 mins
Maintenance dose: 0.7 mcg/kg/hr Intravenous till endotracheal tube is secured
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