Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Eloxatin
Synonyms :
oxaliplatin
Class :
Antineoplastic Agent, Alkylating Agent & Platinum Analog
Brand Name :
Eloxatin
Synonyms :
oxaliplatin
Class :
Antineoplastic Agent, Alkylating Agent & Platinum Analog
Dosage forms & Strengths:Â
Powder for InjectionÂ
50 mg/vialÂ
100 mg/vialÂ
200 mg/vialÂ
Advanced stage of colorectal carcinoma:
Day 1: 85 mg/m² Oxaliplatin Intravenous (IV) + 200 mg/m² leucovorin Intravenous (IV) infused over 2 hours
Following 5-FU 400 mg/m² Intravenous (IV) bolus over 2-4 minutes
Next 5-FU 600 mg/m² Intravenous (IV) infusion over 22 hours
Day 2: WITHOUT oxaliplatin following Same regimen
continue for every 2 weeks
Adjuvant stage III colon cancer:
Course is 12 cycles
continue every 2 weeks,with the above scheduled dose for 6 months
Tumour excision is followed by adjuvant therapy
Safety and efficacy are not seen in pediatrics.Â
Refer adult dosing
oxaliplatin and loperamide are both known to elevate the QTc interval
when both drugs are combined, there may be an increased risk or severity of adverse effects  
when used together, azithromycin and oxaliplatin both increase the QTc interval
pneumococcal vaccine polyvalentÂ
the activity of pneumococcal vaccine polyvalent is reduced due to pharmacodynamic antagonism
When loracarbef is used together with oxaliplatin, the risk or seriousness of nephrotoxicity is enhanced
When oxaliplatin is used in combination with rabies vaccine, this leads to a reduction in the rabies vaccine effects through the process of pharmacodynamic antagonism
may diminish the pharmacodynamic antagonistic effect of each other when combined
measles, mumps, rubella, and varicella vaccine, live 
may diminish the pharmacodynamic antagonistic effect of each other when combined
measles mumps and rubella vaccine, live
may diminish the pharmacodynamic antagonistic effect of each other when combined
may diminish the pharmacodynamic antagonistic effect of each other when combined
smallpox (vaccinia) vaccine, live
may diminish the pharmacodynamic antagonistic effect of each other when combined
By synergism effects, the toxicity of the other drug increases.
when both drugs combine the toxicity of both drugs increases by synergism
when both the drugs are combined, the risk or severity of adverse effects increases    
when both drugs are combined, there may be an increased risk of serious infections  
risk of severe infection due to immunosuppressive effects
may enhance immunosuppression and myelosuppression
Frequency defined
10%
Anemia Â
Nausea Â
Fatigue Â
Diarrhea Â
Vomiting Â
Abdominal pain Â
Constipation Â
Thrombocytopenia Â
Fever Â
Anorexia Â
Leukopenia Â
Dyspnea Â
CoughÂ
1-10%:Â
Edema Â
Neutropenia Â
Pharyngolaryngeal dysesthesiaÂ
<1%:Â
Pulmonary fibrosisÂ
None
oxaliplatin is contraindicated in patients hypersensitive to the active ingredient.Â
Pregnancy consideration:Â Â
No data is available regarding any fetal defects caused due to drug intake during pregnancy.Â
Breastfeeding warnings:Â Â
No data is available regarding the excretion of the drug in breast milk.Â
Pregnancy category:Â
Patient information leaflet:
Generic Name: oxaliplatin
Pronounced: ok-SA-lih-pla-tin
Why do we use oxaliplatin?Â
oxaliplatin is a chemotherapy medication used in the treatment of certain types of cancer. It is specifically utilized in combination with other drugs as part of a treatment regimen for advanced colorectal cancer.
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