2025 Guidelines for the Evaluation and Management of Adults With Congenital Heart Disease
December 19, 2025
Free CME credits
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Brand Name :
N/A
Synonyms :
abicipar pegol
Class :
Ophthalmic, VEGF Inhibitors, Macular Degeneration Agents
Brand Name :
N/A
Synonyms :
abicipar pegol
Class :
Ophthalmic, VEGF Inhibitors, Macular Degeneration Agents
Age-related Neovascular Macular Degeneration
FDA Approval Pending for exudative age-related macular degeneration (AMD)
Not suggested
Refer to adult dosing
Actions and Spectrum
The action of abicipar pegol involves binding to VEGF-A (vascular endothelial growth factor (VEGF) and preventing it from interacting with its receptors on blood vessels.
None
Black Box Warning:
None
Contraindication/Caution:
None
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
The purpose of abicipar pegol is to bind with and block the function of VEGF-A.
abicipar pegol helps treat neovascular age-related macular degeneration by inhibiting VEGF-A, which helps stop the development of new blood vessels and lessens vascular leakage.
Pharmacodynamics
The pharmacodynamic effect of abicipar pegol is its ability to reduce angiogenesis in the eye.
Pharmacokinetics
Limited information available on ADME
Administration
abicipar pegol is administered through intravitreal injection i.e., injected directly into the vitreous humor of the eye.
Patient information leaflet
Generic Name: abicipar pegol (FDA Approval Pending)
Why do we use abicipar pegol?
abicipar pegol is primarily used in the treatment of neovascular (wet) age-related macular degeneration (AMD).
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
