Performance Comparison of Microfluidic and Immunomagnetic Platforms for Pancreatic CTC Enrichment
November 15, 2025
Brand Name :
Miochol E
Synonyms :
acetylcholine
Class :
cholinergic agonists and choline esters
Dosage Forms & Strengths
Powder for injection
20mg
During Ocular Surgery:
0.5 - 2
ml
intraocular instilled during surgery
Miosis of the iris occurs in seconds during surgery
During cataract surgery, this drug should be used only after delivery of the lens.
During Ocular Surgery:
0.5 - 2
ml
intraocular instilled during surgery
Miosis of the iris occurs in seconds during surgery
During cataract surgery, this drug should be used only after delivery of the lens.
Safety and efficacy not established
It may diminish the metabolism when combined with Choline esters
It may diminish the metabolism when combined with Choline esters
It may diminish the metabolism when combined with Choline esters
It may diminish the metabolism when combined with Choline esters
When acetylcholine is used together with paraoxon, this leads to enhanced risk or seriousness of adverse events
When acetylcholine is used together with pegvisomant, this leads to enhanced risk or seriousness of adverse events
when combined with acetylcholine, there is an increased risk or severity of adverse effects associated with ambenonium
When acetylcholine is used together with profenamine, this leads to enhanced risk or seriousness of adverse events
may have an increasingly adverse effects when combined with acetylcholine
the risk of adverse effects may be increased
the risk of adverse effects may be increased
the risk of adverse effects may be increased
the risk of adverse effects may be increased
the risk of adverse effects may be increased
the risk of adverse effects may be increased when cinchocaine is combined with acetylcholine
the anticholinergic activities of cimetropium may be reduced by acetylcholine
Acetylcholine (ACh) is an essential neurotransmitter in the peripheral and central nervous systems.
It has an important role in transmission of nerve impulses across synapses and neuromuscular junctions.
The neuromuscular junction releases acetylcholine, which attaches to nicotinic receptors on skeletal muscle fibers.
It is released from preganglionic and postganglionic parasympathetic fibers.
Adverse drug reactions:
Frequency Not Defined
Corneal clouding
Corneal edema
Corneal decompensation
Sweating
Hypotension
Flushing
Bradycardia
Breathing difficulty
Contraindication:
Hypersensitivity
Caution:
Bradycardia
Hypotension
Bronchoconstriction
GI Hyperactivity
Pregnancy warnings:
A
U TGA pregnancy category: B2
US FDA pregnancy category: Not assigned
Breastfeeding warnings:
The release of the drug into the human breastmilk is unknown
Pregnancy Categories:
Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester.
Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits
Category X: Drugs listed in this category outweigh risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Acetylcholine acts at nicotinic receptors in sympathetic ganglia.
The enzyme choline acetyltransferase in nerve terminals produces this cholinergic neurotransmitter from choline and acetyl-CoA. The enzyme choline acetyltransferase in nerve terminals produces this cholinergic neurotransmitter from choline and acetyl-CoA.
The autonomic ganglia, the adrenal medulla, and the neuromuscular junction of skeletal muscles all contain ligand-gated ion channels called nicotinic receptors.
For Ophthalmic:
Prior to irrigating the eye, attach the filter. Before or after fastening one or more sutures, gently inject into the anterior chamber, tangential to the pupil border and parallel to the iris face.
Acetylcholine should only be administered following lens delivery in cataract surgery.
Patient information leaflet
Generic Name: acetylcholine
Why do we use acetylcholine?
Acetylcholine is used in miosis during ocular surgery.
It is used in cataract surgery, penetrating keratoplasty, iridectomy, and other anterior segment surgeries where quick miosis may be necessary to achieve iris miosis within seconds after lens administration.