Impact of High-Pillow Sleeping Posture on Intraocular Pressure in Glaucoma
January 28, 2026
Brand Name :
Soriatane CK, Soriatane
Synonyms :
acitretin
Class :
Antipsoriatics
Dosage Forms & Strengths
Capsule
10mg
25mg
25-50 mg orally every day
Note: off-label
Indicated for palmoplantar pustulosis, Darier's disease, Sjogren-Larsson syndrome, lichen planus
When both drugs are combined, there may be an increased intracranial pressure
when both drugs are combined, there may be increased toxicity of sarecycline
when both drugs are combined, there may be increased toxicity of omadacycline
the activity of norethisterone is effected by acitretin
metronidazole/tetracycline/bismuth subsalicylate
acitretin, when combined with tetracyclines, can cause an increase in intracranial pressure
may enhance the hepatotoxic adverse effects of trimetrexate
the toxicity of either of the drugs is increased due to pharmacokinetic synergism
the toxicity of either of the drugs is increased due to pharmacokinetic synergism
the therapeutic activity of norethynodrel may be reduced
Adverse drug reactions
Frequency Defined
>10%
arthralgia (10-25%)
Dry mouth (10-25%)
Hepatotoxicity (10-25%)
Hypertriglyceridemia (50-75%)
Cheilitis (>75%)
Alopecia (50-75%)
Dry skin (25-50%)
Dysglycemia (25-50%)
Skin peeling (50-75%)
Increased LFT (25-50%)
Nail disorder (25-50%)
Epistaxis (10-25%)
Hyperesthesia (10-25%)
Paresthesia (10-25%)
Paronychia (10-25%)
Erythematous rash (10-25%)
Pruritus (25-50%)
Rhinitis (25-50%)
Xerophthalmia (10-25%)
1-10%
Somnolence
Nausea
Stomatitis
Vomiting
Abdominal pain
Anorexia
Flushing
Depression
Fatigue
Diarrhea
Gingivitis
Increased appetite
Edema
Headache
Insomnia
Pregnancy warnings:
AU TGA pregnancy category: X
US FDA pregnancy category: X
Lactation:
Excreted into human milk is known
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were no enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Patient Information Leaflet
Generic Name: acitretin
Why do we use acitretin?
acitretin is an Antipsoriatics agent used to treat Psoriasis.