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Brand Name :
N/A
Synonyms :
allyl alcohol
Class :
Primary alcohols, unsaturated alcohols
Dosage forms and strength Â
PlasticizersÂ
Allyl alcohol is a colorless liquid, and a potent sensory irritant. They are used in the production of allyl esters for use in resins and plasticizers.Â
It is a colorless liquid, and a potent sensory irritant
They are used in the production of allyl esters for use in resins and plasticizers as a flavoring agent
Not determined Â
Actions and spectrum:Â Â
The toxic effects of allyl alcohol are due to its metabolic product called acrolein.Â
It is metabolized through two oxidative pathways which lead to the formation of acrolein and epoxide glycidol.Â
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Adverse reaction Â
None Â
Black box warning Â
None Â
Contraindication/Caution:Â Â
None Â
Pregnancy Warnings:
Pregnancy category: N/AÂ
Lactation: Excretion of the drug into the human breast milk is unknownÂ
Pregnancy categories:Â
Category A: Satisfactory and well-controlled studies show no evidence of risk to the fetus in the first trimester or in the later trimester.Â
Category B: No evidence of risk to fetus found in animal reproduction studies and there are not enough studies on pregnant women.Â
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women.Â
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits.Â
Category X: Drugs listed in this category clearly outweigh risks over benefits. These category drugs should be prohibited for pregnant women.Â
Category N: There is no data available for the drug under this category.Â
Pharmacology:Â Â
Allyl alcohol is a primary alcohol. The conversion of allyl alcohol into acrolein is carried by alcohol dehydrogenase (ADH).Â
Pharmacodynamics:Â Â
Limited data is available. Â
Pharmacokinetics:Â Â
Limited data is available on ADME. Â
Administration Â
Not known Â
Patient information leaflet Â
Generic Name: allyl alcohol Â
Why do we use allyl alcohol? Â
Allyl alcohol is used as a fungicide and herbicide. Â
It is also indicated in plastics, resins, plasticizers and in the production of glycerol and acrolein as a flavoring agent.Â