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Brand Name :
Dermadew Aloe
Synonyms :
aloe vera gel/jojoba/vitamin e/glycerine
Class :
Emollients & Skin Protectives
Brand Name :
Dermadew Aloe
Synonyms :
aloe vera gel/jojoba/vitamin e/glycerine
Class :
Emollients & Skin Protectives
Dosage Forms & Strengths
Cream
50 gm
Apply on face and neck daily
Apply on face and neck daily
Refer to adult dosing
Actions and Spectrum
aloe vera gel is known for its soothing and moisturizing properties. aloe vera contains compounds that have anti-inflammatory and antimicrobial effects, which can aid in reducing redness and swelling and promoting skin healing.
jojoba oil is a natural oil extracted from the seeds of the jojoba plant. It is similar in composition to the natural oils produced by our skin, making it an excellent moisturizer.
vitamin E is an antioxidant that helps protect the skin from damage caused by free radicals and UV radiation. It is used in skincare products for its ability to moisturize, promote skin healing, and reduce the appearance of scars and fine lines.
glycerin is a humectant, which means it attracts and retains moisture. It is used in skincare products to help hydrate the skin by drawing water from the environment and locking it into the skin’s outermost layer.
Frequency not defined
Blurred vision
Burning
Confusion
Dehydration
Diarrhea
Black Box Warning
None
Contraindication/Caution:
None
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
<b>Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
aloe vera gel contains various bioactive compounds, including polysaccharides, anthraquinones, and phytosterols. It is known for its anti-inflammatory, moisturizing, and wound-healing properties.
jojoba oil is a natural plant oil closely resembling the skin’s sebum. It acts as a moisturizer and emollient, forming a protective barrier on the skin’s surface.
vitamin E, in the form of tocopherol, is an antioxidant that protects skin cells from oxidative damage caused by free radicals and UV radiation.
glycerine is a humectant, which means it attracts and retains moisture. It forms hydrogen bonds with water molecules, effectively hydrating the skin.
Pharmacodynamics
aloe vera gel can soothe and calm irritated skin through its anti-inflammatory properties. It moisturizes the skin by forming a protective barrier.
jojoba oil can hydrate and moisturize the skin by preventing water loss also control excessive oiliness in individuals with oily skin.
vitamin E can protect the skin from UV-induced damage and oxidative stress and reduce inflammation and redness.
glycerin can moisturize and hydrate the skin by attracting and retaining moisture and improve the skin’s barrier function, reducing dryness and flakiness.
Pharmacokinetics
Absorption
aloe vera gel can be absorbed through the skin to a limited extent.
jojoba oil and glycerine are not absorbed into systemic circulation.
vitamin E can be absorbed through the skin.
Distribution
aloe vera gel is distributed within the skin’s layers.
jojoba oil remains within the skin’s epidermis and forms a protective layer on the skin’s surface.
vitamin E is distributed within the skin.
glycerine remains within the epidermis.
Metabolism
aloe vera’s bioactive components may undergo enzymatic reactions within the skin cells.
jojoba oil is not metabolized by the body when used topically. Its primary role is to act as an emollient and moisturizer on the skin.
vitamin E undergoes metabolism within the skin cells.
glycerin does not undergo metabolism within the skin.
Elimination and excretion
Excretion is not fully understood for aloe vera gel/jojoba/vitamin e/glycerine
Administration
aloe vera gel/jojoba/vitamin e/glycerine all are applied topically to the skin.
These are available in moisturizers, lotions, and creams form.
Patient information leaflet
Generic Name: aloe vera gel/jojoba/vitamin e/glycerine
Why do we use aloe vera gel/jojoba/vitamin e/glycerine?
aloe vera is well-known for its ability to relieve sunburned skin.
aloe vera gel is an excellent natural moisturizer that can help hydrate and nourish the skin, making it softer and smoother.
jojoba oil help soothe and moisturize the scalp, potentially reducing dandruff and flakiness.
jojoba oil can be used to soften and moisturize cuticles, promoting healthy nail growth.
vitamin E is used to minimize the appearance of scars, including surgical scars and stretch marks.
vitamin E may contribute to improved skin tone and complexion.
glycerine helps improve the skin’s natural barrier function, preventing moisture loss and protecting against external irritants.
glycerine is used in lip balms to keep lips hydrated and prevent chapping.
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