aloe vera gel/vitamin e/lactic acid

Action and Spectrum

Actions and Spectrum 

aloe vera gel is known for its soothing and moisturizing properties. aloe vera contains compounds that have anti-inflammatory and antimicrobial effects, which can aid in reducing redness and swelling and promoting skin healing. 

vitamin E is an antioxidant that helps protect the skin from damage caused by free radicals and UV radiation.  

lactic acid is an alpha hydroxy acid (AHA) that is used in skincare for its exfoliating properties. When applied to the skin, it helps to remove dead skin cells, promoting a smoother and brighter complexion.

Drug Interaction

Adverse Reaction

Frequency not defined  

Fatigue 

Headache 

Nausea 

Rash 

Black Box Warning

Black Box Warning 

None

Contraindication / Caution

Contraindication/Caution: 

None

Pregnancy / Lactation

Pregnancy consideration: 

Pregnancy category: N/A 

Lactation: Excretion into human milk is unknown  

Pregnancy Categories:         

Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester. 

<b>Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.  

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women. 

Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits. 

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women. 

Category N: There is no data available for the drug under this category. 

Pharmacology

Pharmacology  

aloe vera gel contains various bioactive compounds, including polysaccharides, anthraquinones, and phytosterols. It is known for its anti-inflammatory, moisturizing, and wound-healing properties.  

vitamin E, in the form of tocopherol, is an antioxidant that protects skin cells from oxidative damage caused by free radicals and UV radiation.  

lactic acid acts as an exfoliant by loosening and removing dead skin cells on the surface. It can stimulate collagen production, improve skin texture, and enhance skin hydration. 

Pharmacodynamics 

aloe vera gel can soothe and calm irritated skin through its anti-inflammatory properties. It moisturizes the skin by forming a protective barrier. 

vitamin E can protect the skin from UV-induced damage and oxidative stress and reduce inflammation and redness. 

lactic acid is an alpha hydroxy acid (AHA) that exfoliates the skin. It works by loosening and breaking down the bonds between dead skin cells, facilitating their removal. 

Pharmacokinetics 

Absorption   

aloe vera gel can be absorbed through the skin to a limited extent. 

vitamin E can be absorbed through the skin.  

lactic acid is absorbed through the skin. 

Distribution 

aloe vera gel is distributed within the skin’s layers. 

vitamin E is distributed within the skin. 

lactic acid remains within the skin tissues. 

Metabolism 

aloe vera’s bioactive components may undergo enzymatic reactions within the skin cells. 

vitamin E and lactic acid both undergoes metabolism within the skin cells.   

Elimination and excretion 

Excretion is not fully understood for aloe vera gel/vitamin e/lactic acid 

Adminstartion

Administration 

aloe vera gel/vitamin e/lactic acid all are applied topically to the skin. 

These are available in moisturizers, lotions, and creams form. 

Patient Information Leaflet

Patient information leaflet 

Generic Name: aloe vera gel/vitamin e/lactic acid 

Why do we use aloe vera gel/vitamin e/lactic acid? 

aloe vera is well-known for its ability to relieve sunburned skin.   

aloe vera gel is an excellent natural moisturizer that can help hydrate and nourish the skin, making it softer and smoother.  

vitamin E is used to minimize the appearance of scars, including surgical scars and stretch marks.  

vitamin E may contribute to improved skin tone and complexion.  

lactic acid is used in skincare products to exfoliate the skin, helping to remove dead skin cells and improve skin texture.  

lactic acid is effective in fading hyperpigmentation, including age spots and uneven skin tone.