androstenetrione

Action and Spectrum

Actions and spectrum:  

Action:
Androstenetrione inhibits aromatase, which converts testosterone to estrogen.
By blocking this conversion, it elevates testosterone levels in the bloodstream. 

Drug Interaction

Adverse Reaction

Frequency not defined  

Cardiac issues  

Hepatic failure  

Mood swings  

Cardiomegaly  

Gynaecomastia  

Shrinking testicles in male  

Increased risk of stroke and blood clots  

Elevated lipid profile  

Enlarged clitoris  

Amenorrhea  

Reduced breast size 

Black Box Warning

Black box warning 

None  

Contraindication / Caution

Contraindication/Caution:  

Contraindication:  

Hypersensitivity  

Caution:  

Prostate cancer  

Liver disease  

Hypertension  

Dyslipidemia  

PCOS  

Diabetes mellitus 

Pregnancy & breast-feeding 

Pregnancy / Lactation

Pregnancy/Lactation 

Pregnancy consideration:   

Data about the use of androstenetrione in pregnancy is not known.  

Lactation:   

Data about the excretion of androstenetrione into human milk has yet to be studied.  

Pregnancy category:   

Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.  

<b>Category B: There was a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.    

Category C: There was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.     

Category D: Adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.    

Category X: Drugs listed in this category outweigh the risks over benefits. Hence, these categories of drugs need to be avoided by pregnant women.     

Category N: There is no data available for the drug under this category 

Pharmacology

Pharmacology:  

Androstenetrione is an anabolic steroid.  

Pharmacodynamics:  

Androstenetrione inhibits aromatase, which converts testosterone to estrogen.
By blocking this conversion, it elevates testosterone levels in the bloodstream. 

Pharmacokinetics:  

Limited data available 

Adminstartion

Administration:  

To be administered as advised by the physician 

Patient Information Leaflet

Patient information leaflet  

Generic Name: androstenetrione  

Why do we use androstenetrione?  

Androstenetrione is used to enhance athlete performance, strength & muscle mass.