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Brand Name :
Leritine
Synonyms :
anileridine phosphate
Class :
Opioid Analgesic
Brand Name :
Leritine
Synonyms :
anileridine phosphate
Class :
Opioid Analgesic
Dosage Forms & Strengths
Tablet
25 mg
50 mg
Take a dose of 25 to 50 mg orally and repeat every 6 hours if required
Take a dose 25 to 50 mg subcutaneously or intramuscularly and repeat every 4 to 6 hours
Dose not more than 200 mg in a day
Not determined
Refer to adult dosing
Actions and Spectrum
anileridine phosphate binds to opioid receptors in the brain and spinal cord. These receptors are part of the body’s natural pain control system. By binding to these receptors, anileridine phosphate reduces the transmission of pain signals and alters the perception of pain.
Frequency not defined
Dizziness
Restlessness
Nervousness
Dry mouth
Visual difficulty
Perspiration
Euphoria
Feeling of warmth
Itching
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
anileridine phosphate binds to specific receptors called opioid receptors in the brain and spinal cord. These receptors are part of the body’s natural pain control system.
Pharmacodynamics
anileridine phosphate acts as an agonist at various opioid receptors, with a primary affinity for the mu-opioid receptor.
Pharmacokinetics
Absorption
anileridine phosphate is absorbed through the gastrointestinal tract after oral administration.
Distribution
anileridine phosphate is distributed throughout the body via the bloodstream.
Metabolism
anileridine phosphate undergoes metabolism primarily in the liver, where it is metabolized by various enzymatic pathways.
Elimination and excretion
anileridine phosphate is eliminated from the body mainly through the urine.
Administration
anileridine phosphate is typically administered via oral or parenteral (subcutaneous or intramuscular) routes.
Patient information leaflet
Generic Name: anileridine phosphate
Why do we use anileridine phosphate?
anileridine phosphate is used in management of moderate to severe pain such as angina pectoris, renal colic, biliary colic, and pain associated with extensive burns.
anileridine phosphate may be used to manage acute pain episodes, such as pain resulting from injuries, trauma, or medical procedures.
anileridine phosphate is used in acute congestive heart failure for rest and relief of apprehension and in oral surgery for relief of pain including that of exodontia.
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