DRUG INTERACTION

Contraindicated  

Serious Use Alternative  

Monitor Closely  

Minor  

Adverse drug reactions:   

>10%  

Headache (12%)  

Dizziness (11%)  

Somnolence (24%)  

Pediatric patients  

Somnolence (49%)  

Oral paraesthesia (27%)  

1-10%  

Akathisia (4%)  

Oral hypoesthesia (4%)  

Dry mouth (3%)  

Dysgeusia (3%)  

Insomnia (6%)  

Weight gain (5%)  

Dyspepsia (4%)  

Anxiety (4%)  

Fatigue (4%)  

  

  

  

Pregnancy warnings:     

AU TGA pregnancy category: C 

US FDA pregnancy category: N/A 

Lactation: 

Excreted into human milk is UNknown 

Pregnancy Categories:       

Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester.       

Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women       

Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women       

Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.       

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.       

Category N: There is no data available for the drug under this category 

Patient Information Leaflet    

Generic Name: asenapine 

Why do we use asenapine? 

asenapine are an Antipsychotics, 2nd Generation used to treat Schizophrenia and bipolar disorder.