atorvastatin and ezetimibe

Action and Spectrum

Drug Interaction

Adverse Reaction

Frequency defined:  

Abdominal or stomach pain 

confusion 

difficult breathing 

difficulty with moving 

irregular heartbeat 

muscle, joint, or bone pain 

muscle stiffness 

muscle weakness 

nausea or vomiting 

nervousness 

numbness in the hands and feets 

weakness or heaviness of the legs 

Black Box Warning

Contraindication / Caution

Pregnancy / Lactation

Pregnancy consideration: The safety of the drug is not established during pregnancy  

Lactation: The excretion of the drug in human breast milk is unknown  

Pregnancy category: 

• Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester. 
• Category B: There is no evidence of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women. 
• Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women 
• Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits. 
• Category X: Drugs listed in this category outweigh risks over benefits These category drugs should be prohibited for pregnant women. 
• Category N: No data is available for the drug under this category. 

Pharmacology

Adminstartion

Patient Information Leaflet

Patient information leaflet 

Generic Name: atorvastatin and ezetimibe 

Pronounced: a-tore-va-stat-in/e-zet-i-mibe 

Why do we use atorvastatin and ezetimibe? 

Atorvastatin and ezetimibe are used to treat high cholesterol and high triglycerides levels in the blood