Digital Monitoring Uncovers the Long-Term Neurological Impact of COVID-19
January 16, 2026
Brand Name :
Alphatrex, Dermabet, Diprolene AF, Luxiq
Synonyms :
betamethasone topical
Class :
Corticosteroids, Topical
Dosage Forms & Strengths
Foam
0.12%
Gel
0.05%
Cream/lotion/ointment
0.05%
0.1%
Spray
0.05%
Dosage Forms & Strengths
Foam
0.12%
Gel
0.05%
Cream/lotion/ointment
0.05%
0.1%
Spray
0.05%
Refer adult dosing
the activity of the anthrax vaccine can be reduced when used in combination with betamethasone
Corticosteroids can directly bind to leukocyte lysosomal membrane and prevent any breakup of membranes and subsequent release of destructive action of acid hydrolases. They also inhibit accumulation of macrophages in the inflamed site, reduce adhesion of leukocyte to capillary endothelium thus reducing capillary permeability and edema formation.
Frequency Not Defined
Allergic dermatitis
Striae
Burning
Skin atrophy
Erythema folliculitis
Dry skin
Hypertrichosis
Miliaria
Irritation
Vesiculation
Pigmentation changes
Acneform lesions
Prolonged use of these medications can lead to skin atrophy, striae (stretch marks), telangiectasia (dilated blood vessels) and acne
Hypersensitivity
Skin infections
Acne
Pregnancy/Lactation
Pregnancy warnings:
Pregnancy category: Insufficient data available
Lactation: Excreted into human milk is unknown
Pregnancy Categories:
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.
Category B: There were lack of studies on pregnant women and no evidence of risk to the foetus in animal experiments.
Category C: there was evidence of risk of adverse effects in animal reproduction studies and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms but despite the potential risk and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
It works by inhibiting the inflammatory cytokines which thereby reduces the inflammation and used to treat skin conditions.
Pharmacodynamics
It has anti-inflammatory and anti-pruritic effect
Pharmacokinetics
Absorption
When applied topically it is absorbed evenly
Distribution
It is widely distributed throughout the body
Metabolism
It undergoes hepatic metabolism by the cytochrome P450 (CYP) 3A4 enzyme. Metabolites are excreted in the urine and feces.
Elimination and Excretion
It undergoes excretion through kidney and has a half-life of 36 to 54 hours.
It is administered topically in the form of ointment and lotions
Patient Information Leaflet
Generic Name: betamethasone topical
Why do we use betamethasone topical?
Topical betamethasone is an active compound belonging to the corticosteroid class with anti-inflammatory action that can be applied for the treatment of several skin diseases. Here are the primary uses of betamethasone topical:
Psoriasis: Helps to minimize pain, swelling, redness and scaling which accompany plaque-type psoriasis.
Eczema (Atopic Dermatitis): Helps to relieve itching, redness, and inflammation of the skin during flare-ups of eczema.
Contact Dermatitis: Effectively manages symptoms of skin rash which maybe caused by allergens or irritants.
Seborrheic Dermatitis: Used in the management of seborrheic dermatitis especially in the scalp and facial areas.