- March 15, 2022
- Newsletter
- 617-430-5616
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Brand Name :
Devrom
Synonyms :
bismuth subgallate
Class :
Gastrointestinal Agents
Dosage Forms & Strengths
Tablet
200 mg
Swallow or chew 200 to 400 mg orally three times daily with food
Dosage Forms & Strengths
Tablet
200 mg
Swallow or chew 200 mg orally three times daily with food
Refer to adult dosing
may decrease the therapeutic effect of anticholinergic agents
it may reduce the therapeutic effect of gastrointestinal agents
it may reduce the therapeutic effect of gastrointestinal agents
it may reduce the therapeutic effect of gastrointestinal agents
anti-cholinergic agents may diminish the therapeutic effect of gastrointestinal agents
anti-cholinergic agents may diminish the therapeutic effect of gastrointestinal agents
anti-cholinergic agents may diminish the therapeutic effect of gastrointestinal agents
anti-cholinergic agents may diminish the therapeutic effect of gastrointestinal agents
anti-cholinergic agents may diminish the therapeutic effect of gastrointestinal agents
may reduce the therapeutic effect
may reduce the therapeutic effect
may reduce the therapeutic effect
may reduce the therapeutic effect
anticholinergic agents decrease the efficacy of gastrointestinal agents
anticholinergic agents decrease the efficacy of gastrointestinal agents
anticholinergic agents decrease the efficacy of gastrointestinal agents
anticholinergic agents decrease the efficacy of gastrointestinal agents
anticholinergic agents decrease the efficacy of gastrointestinal agents
It may reduce the therapeutic effect of gastrointestinal agents
It may reduce the therapeutic effect of gastrointestinal agents
It may reduce the therapeutic effect of gastrointestinal agents
It may reduce the therapeutic effect of gastrointestinal agents
It may reduce the therapeutic effect of gastrointestinal agents
it may decrease the levels of serum concentration of Fosfomycin
it may decrease the levels of serum concentration of Sirolimus
may reduce the therapeutic effect of gastrointestinal agents
may reduce the therapeutic effect of gastrointestinal agents
may reduce the therapeutic effect of gastrointestinal agents
may reduce the therapeutic effect of gastrointestinal agents
may reduce the therapeutic effect of gastrointestinal agents
hydrocodone/chlorpheniramine/pseudoephedrine
may diminish the therapeutic effect
may decrease the therapeutic effect
may reduce the therapeutic effect of gastrointestinal agents
may reduce the therapeutic effect of gastrointestinal agents
may reduce the therapeutic effect of gastrointestinal agents
may reduce the therapeutic effect of gastrointestinal agents
may decrease the therapeutic effect of anticholinergic agents
may decrease the therapeutic effect of Anticholinergic Agents
may reduce the effect of gastrointestinal drugs
may reduce the effect of gastrointestinal drugs
may reduce the effect of gastrointestinal drugs
may reduce the effect of gastrointestinal drugs
may reduce the effect of gastrointestinal drugs
may reduce the effect of gastrointestinal drugs
may reduce the effect of gastrointestinal drugs
may reduce the effect of gastrointestinal drugs
may reduce the effect of gastrointestinal drugs
may reduce the effect of gastrointestinal drugs
may decrease the therapeutic effect of Opioid Agonists
buprenorphine,long-acting injection
may decrease the therapeutic effect of Opioid Agonists
acetaminophen/doxylamine/dextromethorphan
may decrease the therapeutic effect of anticholinergic Agents
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
Actions and Spectrum
The digestive tract can absorb fluids and poisons thanks to the absorbent characteristics of bismuth subgallate. In situations of diarrhea, this activity helps to lessen the frequency and liquidness of feces.
bismuth subgallate forms a protective layer over irritated or injured mucous membranes, such as in the gastrointestinal tract. bismuth subgallate acts locally within the gastrointestinal tract and is not absorbed significantly into the bloodstream.
Frequency not defined
Temporary dark or black stool discoloration
Temporary darkening of tongue
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: C
Lactation: Drug is poorly absorbed into system circulation
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
The mechanism of action of bismuth subgallate is not known.
Pharmacodynamics
bismuth subgallate forms a protective layer over irritated or injured mucous membranes.
bismuth subgallate possesses deodorizing properties. It is used to help reduce or eliminate unpleasant odors associated with certain medical conditions, such as fecal or wound odors.
Pharmacokinetics
Absorption
bismuth subgallate is poorly absorbed from the gastrointestinal tract.
Distribution
bismuth subgallate does not exhibit significant distribution throughout the body.
Metabolism
bismuth subgallate is not extensively metabolized in the body.
Elimination and excretion
bismuth subgallate is not significantly eliminated through urine.
Administration
bismuth subgallate is typically administered orally in tablet or capsule form.
Patient information leaflet
Generic Name: bismuth subgallate
Why do we use bismuth subgallate?
bismuth subgallate has been used as an antidiarrheal agent. It can help reduce the frequency and liquidity of stools by absorbing excess fluids and toxins. bismuth subgallate has been used to control and reduce foul odors.