Urological Telesurgery Proves as Reliable as Local Robotic Surgery in Randomised Trial
February 6, 2026
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Brand Name :
Brovex PB, Respahist-II, Children's Dimetapp Cold & Allergy Vazotab Chewable
Synonyms :
brompheniramine phenylephrine
Class :
Antihistamine/Decongestant Combos
Brand Name :
Brovex PB, Respahist-II, Children's Dimetapp Cold & Allergy Vazotab Chewable
Synonyms :
brompheniramine phenylephrine
Class :
Antihistamine/Decongestant Combos
Dosage Forms & Strengths
Tablet, chewable
6mg/15mg
Oral liquid
(1mg/2.5mg)/5mL
(2mg/5mg)/5mL
Oral suspension
(6mg/10mg)/5mL
(1.2mg/2mg)/1mL
Elixir
(1mg/2.5mg)/5mL
(1.2 mg/2 mg)/1 mL] orally every 4-6 hours as 3 ml of solution
Do not exceed the dose of more than 18 mL/24 hour
[(4 mg/10 mg)/5 mL] orally every 4-6 hours as a 5 ml solution
Do not exceed the dose of more than 30 mL/24 hour
[(1mg/2.5mg)/5mL] orally every 4-6 hours as 20 ml solution
Do not exceed more than 120 mL/24 hour
Dosage Forms & Strengths
Tablet, chewable
1mg/2.5mmg
6mg/15mg
Oral liquid
(1mg/2.5mg)/5mL
(2mg/5mg)/5mL
Oral suspension
(6mg/10mg)/5mL
(1.2mg/2mg)/1mL
Elixir
(1mg/2.5mg)/5mL
For more than 12 years- [(1.2 mg/2 mg)/1 mL] orally every 4-6 hours as 3 ml of solution
Do not exceed the dose of more than 18 mL/24 hour
For 6-12 years- [(1mg/2.5mg)/5mL] orally every 4-6 hours as 10 ml solution
Do not exceed more than 120 mL/24 hour
Refer to the adult dosing
may enhance the serum concentration when combined
acetaminophen/doxylamine/dextromethorphan
may enhance the serum concentration when combined
Actions and Spectrum:
brompheniramine works by eliciting high anti-allergic activity. It also shows low sedation and optimum anticholinergic effect.
phenylephrine acts as a decongestant and vasoconstrictor. It collapses the swollen membranes, thereby reducing tissue hyperemia and nasal congestion.
Frequency not defined
Dizziness
Anxiety
Nervousness
Headache
Restlessness
Reflex bradycardia
Hypertension
Rebound congestion
Stomach upset
Constipation
Black Box Warning:
None
Contraindication/Caution:
Contraindications
Cautions
Pregnancy consideration:
Category C. The drug is contraindicated during 1st trimester and last 14 days of pregnancy.
Breastfeeding warnings:
The drug is contraindicated during lactation.
Pregnancy category:
Category A: well-controlled and satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: No data is available for the drug under this category.
Pharmacology:
brompheniramine is an antihistamine drug that blocks the effects of histamine, a chemical released during allergic reactions. It acts as a competitive antagonist at histamine H1 receptors, preventing histamine from binding to and activating these receptors.
phenylephrine is a sympathomimetic drug that acts as a selective alpha-1 adrenergic receptor agonist. It stimulates the alpha-1 adrenergic receptors on blood vessels, causing vasoconstriction (narrowing blood vessels) and reducing nasal congestion.
Pharmacodynamics:
Pharmacodynamics includes receptor interactions, enzyme interactions, signal transduction pathways, and dose-response relationships.
Pharmacokinetics:
Absorption
The onset takes place in 15-30 min
The duration of action is achieved in 3-9 hours (brompheniramine) and 2-4 hours (phenylephrine)
The peak plasma concentration is attained in 2-5 hr (brompheniramine)
Distribution
The volume of distribution is 11.7 L/kg
Metabolism
MAO inhibitors metabolize brompheniramine in the liver and phenylephrine in the intestine.
Elimination and Excretion
The half-life is 11.8-34.7 hours and is excreted in the urine
Administration:
brompheniramine and phenylephrine are administered through the oral route. It is provided in oral solutions, elixirs, suspension, and chewable tablets.
Patient information leaflet
Generic Name: brompheniramine/phenylephrine
Pronounced: BROM-fen-IR-a-meen-and-FEN-il-EFF-rin
Why do we use brompheniramine/phenylephrine?
brompheniramine/phenylephrine is a nasal decongestant used to relieve respiratory tract congestion, rhinitis, and allergic rhinitis.
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