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canagliflozin is a medication that belongs to a class of drugs known as sodium-glucose cotransporter 2 (SGLT2) inhibitors. It is primarily used to treat type 2 diabetes alone or in combination with other medications, diet, and exercise.
The drug works by inhibiting SGLT2, a protein in the kidneys that helps to reabsorb glucose back into the bloodstream. By blocking SGLT2, canagliflozin prevents the kidneys from reabsorbing glucose, leading to increased urinary excretion of glucose and reduced blood sugar levels.
In addition to its glucose-lowering effects, canagliflozin has other benefits, including weight loss and blood pressure reduction. It has been shown to improve cardiovascular outcomes in patients with type 2 diabetes with a high risk of cardiovascular disease.
canagliflozin is usually taken orally once a day, with or without food. It is metabolized in the liver and excreted primarily in the urine.
