carbazochrome

Action and Spectrum

Actions and Spectrum 

carbazochrome is classified as a hemostatic agent. This means it helps in the process of blood clotting, specifically by promoting the aggregation of platelets, which are essential for blood clot formation. Platelets is having role in stopping bleeding by adhering to damaged blood vessels and forming a plug at the site of injury.

Drug Interaction

Adverse Reaction

Frequency not defined  

GI disturbances 

Hypersensitivity 

Black Box Warning

Black Box Warning 

None 

Contraindication / Caution

Contraindication/Caution: 

Contraindication: 

• carbazochrome should not be used in individuals who have a known hypersensitivity or allergy to the active ingredient. 

Caution: 

• Caution in individuals with a history of thrombotic events. 
• Caution should be taken when prescribing carbazochrome to individuals with renal impairment. 

Pregnancy / Lactation

Pregnancy consideration: 

Pregnancy category: N/A 

Lactation: Excretion into human milk is unknown  

Pregnancy Categories:         

Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester. 

<b>Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.  

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women. 

Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits. 

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women. 

Category N: There is no data available for the drug under this category. 

Pharmacology

Pharmacology  

carbazochrome enhances platelet aggregation, which is the clumping together of platelets in the blood. Platelets are essential for forming the initial plug at the site of a blood vessel injury. 

Pharmacodynamics 

carbazochrome may help protect and strengthen the walls of blood vessels, particularly capillaries, which are the smallest blood vessels in the body.  

carbazochrome may reduce the fragility of capillaries, making them less prone to leakage and bleeding. 

Pharmacokinetics 

Absorption   

carbazochrome is absorbed from the gastrointestinal tract.   

Distribution 

carbazochrome is distributed throughout the body. 

Metabolism 

carbazochrome undergoes metabolic processes within the body. 

Elimination and excretion 

carbazochrome from the body occurs through the renal route.

Adminstartion

Administration 

carbazochrome is available in tablet or capsule form for oral administration.  

It also administered through subcutaneous and intramuscular routes.

Patient Information Leaflet

Patient information leaflet 

Generic Name: carbazochrome 

Why do we use carbazochrome?  

carbazochrome is used as a hemostatic agent to help control bleeding in various bleeding disorders.  

carbazochrome indicated for capillary and parenchymal hemorrhage, and thrombocytopenic purpura.