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Brand Name :
Styptochrome, Stadren, Stopcrome
Synonyms :
carbazochrome
Class :
Haemostatic agent
Dosage Forms & Strengths
Tablet
10 mg
Solution
10 mg/ml
Idiopathic Thrombocytopenic Purpura (ITP)
Administer a dose of 10 mg daily through subcutaneous or intramuscular injection
Not determined
Refer to adult dosing
Actions and Spectrum
carbazochrome is classified as a hemostatic agent. This means it helps in the process of blood clotting, specifically by promoting the aggregation of platelets, which are essential for blood clot formation. Platelets is having role in stopping bleeding by adhering to damaged blood vessels and forming a plug at the site of injury.
Frequency not defined
GI disturbances
Hypersensitivity
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
<b>Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
carbazochrome enhances platelet aggregation, which is the clumping together of platelets in the blood. Platelets are essential for forming the initial plug at the site of a blood vessel injury.
Pharmacodynamics
carbazochrome may help protect and strengthen the walls of blood vessels, particularly capillaries, which are the smallest blood vessels in the body.
carbazochrome may reduce the fragility of capillaries, making them less prone to leakage and bleeding.
Pharmacokinetics
Absorption
carbazochrome is absorbed from the gastrointestinal tract.
Distribution
carbazochrome is distributed throughout the body.
Metabolism
carbazochrome undergoes metabolic processes within the body.
Elimination and excretion
carbazochrome from the body occurs through the renal route.
Administration
carbazochrome is available in tablet or capsule form for oral administration.
It also administered through subcutaneous and intramuscular routes.
Patient information leaflet
Generic Name: carbazochrome
Why do we use carbazochrome?
carbazochrome is used as a hemostatic agent to help control bleeding in various bleeding disorders.
carbazochrome indicated for capillary and parenchymal hemorrhage, and thrombocytopenic purpura.