DRUG INTERACTION

Contraindicated  

Serious Use Alternative  

Monitor Closely  

Minor  

Frequency defined:  

>10% 

Weight gain 

Hypotension 

Fatigue 

Diarrhea 

Dizziness 

Hyperglycemia  

1-10% 

Nausea 

Cough 

Headache 

Angina 

Hypercholesterolemia 

Vomiting 

Dyspnea 

Syncope 

Rhinitis 

Bradycardia  

<10% 

Insomnia 

Palpitations 

Impotence 

Rales 

Depression 

Hepatotoxicity 

Impotence 

Raynaud phenomenon  

Post-marketing report 

Urinary incontinence 

Interstitial pneumonitis 

Aplastic anemia 

Urticaria 

Stevens-johnson syndrome 

Be cautious with patients suffering from Chronic obstructive pulmonary disease, myocardial depression, hyperthyroidism, diabetes mellitus, pheochromocytoma, and myasthenia gravis. 

Pregnancy consideration:  

Insufficient data is available  

US FDA pregnancy category: Not assigned  

Lactation:   

The drug is not excreted in the human breast milk  

Pregnancy category: 

• Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester. 
• Category B: There is no evidence of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women. 
• Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women 
• Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits. 
• Category X: Drugs listed in this category outweigh risks over benefits. These category drugs should be prohibited for pregnant women. 
• Category N: There is no data available for the drug under this category. 

 

Patient information leaflet 

Generic Name: Carvedilol 

Pronounced: [ KAR-ve-dil-ole]  

Why do we use carvedilol? 

Carvedilol treats hypertension (high blood pressure) and heart failure.