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Brand Name :
Zerviate
Synonyms :
cetirizine ophthalmic
Class :
Antihistamine, Ophthalmic
Brand Name :
Zerviate
Synonyms :
cetirizine ophthalmic
Class :
Antihistamine, Ophthalmic
Dosage Forms & StrengthsÂ
Ophthalmic solutionÂ
0.24%Â
Put one drop in each affected eye two times a day, with an interval of approximately 8 hours
Dosage Forms & StrengthsÂ
Ophthalmic solutionÂ
0.24%Â
Safety and efficacy not determined in less than two years old
≥2 years:
Put one drop in each affected eye two times a day, with an interval of approximately 8 hours
Refer to adult dosingÂ
Actions and SpectrumÂ
cetirizine ophthalmic is a selective antagonist of histamine H1 receptors. By blocking these receptors, cetirizine inhibits the effects of histamine, which is released during allergic reactions.
Frequency defined Â
1-10%Â
Instillation site pain (1-7%)Â
Hyperemia (1-7%)Â
Reduced visual acuity (1-7%)
Black Box WarningÂ
None
Contraindication/Caution:Â
Contraindication:Â
None Â
Caution:Â
Pregnancy consideration:Â
Pregnancy category: N/AÂ
Lactation: Excretion into human milk is unknown Â
Pregnancy Categories:        Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.Â
Category N: There is no data available for the drug under this category.Â
Pharmacology Â
Histamine-1 receptor antagonist reduces chemotaxis. It prevents eosinophil activation and prevents mast cell release of histamine. Â
PharmacodynamicsÂ
Limited information available Â
PharmacokineticsÂ
Absorption  Â
Limited information available on ADME
AdministrationÂ
cetirizine ophthalmic is usually available in the form of an eye drops.
Patient information leafletÂ
Generic Name: cetirizine ophthalmic Â
Why do we use cetirizine ophthalmic?Â
cetirizine ophthalmic is used to treat itchy eyes caused by allergies. Â
It works by blocking a certain natural substance (histamine) that causes allergic symptoms.