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Brand Name :
Zerviate
Synonyms :
cetirizine ophthalmic
Class :
Antihistamine, Ophthalmic
Brand Name :
Zerviate
Synonyms :
cetirizine ophthalmic
Class :
Antihistamine, Ophthalmic
Dosage Forms & Strengths
Ophthalmic solution
0.24%
Put one drop in each affected eye two times a day, with an interval of approximately 8 hours
Dosage Forms & Strengths
Ophthalmic solution
0.24%
Safety and efficacy not determined in less than two years old
≥2 years:
Put one drop in each affected eye two times a day, with an interval of approximately 8 hours
Refer to adult dosing
Actions and Spectrum
cetirizine ophthalmic is a selective antagonist of histamine H1 receptors. By blocking these receptors, cetirizine inhibits the effects of histamine, which is released during allergic reactions.
Frequency defined
1-10%
Instillation site pain (1-7%)
Hyperemia (1-7%)
Reduced visual acuity (1-7%)
Black Box Warning
None
Contraindication/Caution:
Contraindication:
None
Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
Histamine-1 receptor antagonist reduces chemotaxis. It prevents eosinophil activation and prevents mast cell release of histamine.
Pharmacodynamics
Limited information available
Pharmacokinetics
Absorption
Limited information available on ADME
Administration
cetirizine ophthalmic is usually available in the form of an eye drops.
Patient information leaflet
Generic Name: cetirizine ophthalmic
Why do we use cetirizine ophthalmic?
cetirizine ophthalmic is used to treat itchy eyes caused by allergies.
It works by blocking a certain natural substance (histamine) that causes allergic symptoms.
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