Performance Comparison of Microfluidic and Immunomagnetic Platforms for Pancreatic CTC Enrichment
November 15, 2025
Brand Name :
N/A
Synonyms :
cinalukast
Class :
Anti asthmatic drugs
Dosage Forms & StrengthsÂ
Off-label
In vivo, the study suggests that
0.12mg/kg to be taken orally
(Or)
0.008% as an aerosol
Indications: it is indicated for use in asthma and bronchoconstriction
Dosage Forms & StrengthsÂ
Data not availableÂ
Refer to adult dosingÂ
Action and SpectrumÂ
When arachidonic acid is metabolized it releases the LTE4,LTC4 and LTD4 leukotrienes and binds to their respective receptors named cysteinyl leukotriene receptors.The inhibition of the leukotrienes with receptors help in relaxing the smooth muscles in the human airway and prevents the edema in the airway.Â
Frequency not definedÂ
Adverse effects of cinalukast are not documentedÂ
Black Box Warning Â
No specific black box warnings are available for this drugÂ
Contraindication/Caution:Â
Contraindication:Â
Hypersensitivity
Pregnancy consideration:Â Â
USFDA pregnancy category: Not assignedÂ
Lactation:Â Â
Data about the excretion of cinalukast into human milk has yet to be studied.Â
Pregnancy category:Â Â
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.Â
<b>Category B: There was a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.  Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.  Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence, these categories of drugs need to be avoided by pregnant women.   Â
Category N: There is no data available for the drug under this category
PharmacologyÂ
It is a leukotriene D4 receptor antagonist which protects against the inflammation particularly exercise induced asthma and bronchoconstriction.Â
PharmacodynamicsÂ
It selectively binds to CysLT1 in the human airway, thereby inhibiting LTD4. By blocking LTD4’s activity at the CysLT1 receptor.Â
PharmacokineticsÂ
Data is not available Â
AdministrationÂ
It is taken orallyÂ
Patient information leaflet Â
Generic Name: cinalukast  Â
Why do we use cinalukast? Â
It is a selective LTD4, cysteine leukotriene antagonist and is indicated in the treatment of asthma and bronchoconstriction due to exercise.Â