Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Quarzan
Synonyms :
clidinium
Class :
Anticholinergic agent
Brand Name :
Quarzan
Synonyms :
clidinium
Class :
Anticholinergic agent
Dosage Forms & Strengths Â
Capsule (in combination) Â
clidinium/chlordiazepoxide Â
2.5 mg/ 5mg Â
In conjunction with other medications, clidinium is used to treat gastrointestinal (stomach and intestines) problems such diverticulitis, irritable bowel syndrome, and others that cause cramps and abdominal pain;
Additionally, it is used to treat peptic ulcer disease, which is characterised by burning in the stomach, fullness in the abdomen, nausea, bloating, etc
In combination: In the US, it (2.5 mg) can only be purchased commercially in a set combination with chlordiazepoxide hydrochloride (5 mg)
Individual dosage titration is not possible with fixed-ratio combination medicines; Administration via mouth 3 to 4 times per day
Dose Adjustments
Limited data is available
Irritable Bowel Syndrome (IBS)Â
In conjunction with other medications, clidinium is used to treat gastrointestinal (stomach and intestines) problems such diverticulitis, irritable bowel syndrome, and others that cause cramps and abdominal pain;
Additionally, it is used to treat peptic ulcer disease, which is characterised by burning in the stomach, fullness in the abdomen, nausea, bloating, etc
In combination: In the US, it (2.5 mg) can only be purchased commercially in a set combination with chlordiazepoxide hydrochloride (5 mg). Individual dosage titration is not possible with fixed-ratio combination medicines; Administration via mouth 3 to 4 times per day
Dose Adjustments
Limited data is available
Safety and efficacy are not establishedÂ
Refer to the adult dosingÂ
When clidinium is used together with profenamine, this leads to enhanced risk or seriousness of adverse events
the risk or extent of CNS depression can be raised when clidinium is combined with agomelatine
the risk or extent of adverse effects can be raised when clidinium is combined with alfentanil
the risk or extent of CNS depression can be raised when clidinium is combined with alimemazine
the risk or extent of CNS depression can be raised when clidinium is combined with almotriptan
the risk or extent of tachycardia can be raised when amphetamine is combined with clidinium
the risk or extent of tachycardia can be raised when anagrelide is combined with clidinium
the risk or extent of CNS depression can be raised when apomorphine is combined with clidinium
Actions and Spectrum: Â
Actions: Â
Clidinium relieves muscle spasms and reduces secretions by blocking.Â
Spectrum: Â
Clidinium is useful in treating several gastrointestinal disorders including IBS & peptic ulcer disease.Â
Frequency not defined Â
Constipation Â
Agitation Â
Dry mouth Â
Tachycardia Â
Urinary retention Â
Nervousness Â
Infection Â
Abdominal discomfort Â
Liver abnormalities Â
Black Box Warning: Â
Clidinium worsens symptoms in people with myasthenia gravis.Â
Contraindication/Caution: Â
Contraindications Â
Hypersensitivity Â
Narrow-angle glaucoma Â
Prostatic hypertrophyÂ
Cautions Â
Renal impairment Â
Intestinal obstruction Â
Hepatic impairment Â
Pregnancy & breastfeeding Â
Pregnancy/LactationÂ
Pregnancy consideration:  Â
No data is available regarding the administration of the drug during pregnancy. Â
Breastfeeding warnings:  Â
No data is available regarding the excretion of drug in breast milk. Â
Pregnancy category: Â
Category A: Well-controlled and satisfactory studies show no risk to the fetus in the first or later trimester. Â
<b>Category B: There was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. Â
Category C: There was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.    Â
Category D: Adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.    Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.    Â
Category N: No data is available for the drug under this category. Â
Pharmacology: 
Clidinium treats stomach ulcers & GI disorders by blocking certain nerve signals.Â
Pharmacodynamics: Â
Clidinium relieves muscle spasms and reduces secretions by blocking acetylcholine’s effect on GI tract nerve receptors.Â
Pharmacokinetics: Â
N/A Â
Administration: Â
The route of administration is oral.Â
Patient information leaflet Â
Generic Name: clidinium Â
Pronounced: kli-DIN-ee-um Â
Why do we use clidinium? 
Clidinium is usually combined with chlordiazepoxide to treat conditions like peptic ulcers and IBS by calming excessive gut movement and spasms.Â
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