- July 6, 2022
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Brand Name :
Bactrim DS, Bactrim, Sulfatrim Pediatric
Synonyms :
Trimethoprim-sulfamethoxazole
Class :
Antibiotics, Sulfonamide derivatives
80
mg
Orally
twice a day
4 - 6
weeks
Tablets
160
mg
Orally
twice a day
3
days
Tablet
80
mg
Orally
twice a day
3
days
Tablet
80
mg
Orally
twice a day
5
days
Tablet
antibiotics reduce the efficacy of BCG intravesical
antibiotics reduce the efficacy of the cholera vaccine
trimethoprim enhances the concentration of dofetilide in serum
sulfonamides increase the toxic or adverse effects of mecamylamine
it increases the toxic or adverse effects of methenamine
it may decrease the efficacy of sulfonamide antibiotics
it may decrease the efficacy of sulfonamide antibiotics
sulfonamides increase the toxic or adverse effects of ajmaline
they may increase the hypoglycemic effect of blood-lowering agents
trimethoprim increases the concentration of dapsone in serum
antibiotics reduce the efficacy of estriol and lactobacillus
sulfamethoxazole increases the effect of myelosuppression of mercaptopurine
they may increase the hypoglycemic effect of blood-lowering agents
they may increase the hypoglycemic effect of blood-lowering agents
photosensitizing agents increase the effect of photosensitization of verteporfin
trimethoprim and azithromycin both increase the QTc level when used simultaneously
sulfamethoxazole increases the effect of bosentan by altering hepatic CYP2C9/10 enzyme metabolism
it increases the effect of sulfamethoxazole by altering hepatic CYP2C9/10 enzyme metabolism
sulfamethoxazole increases the effect of ibuprofen by altering hepatic CYP2C9/10 enzyme metabolism
sulfamethoxazole increases the effect of meloxicam by altering hepatic CYP2C9/10 enzyme metabolism
sulfamethoxazole increases the effect of phenytoin by reducing the metabolism
zafirlukast increases the effect of sulfamethoxazole by altering hepatic CYP2C9/10 enzyme metabolism
Frequency undefined:
Anorexia
Nausea
Vomiting
Vertigo
Seizure
Peripheral neuritis
Erythema multiforme
Hyperkalemia
Rash
Urticaria
Stevens-Johnson syndrome
Toxic epidermal necrolysis
Agranulocytosis
Aplastic anemia
Hyponatremia
Fulminant hepatic necrosis
cotrimoxazole is contraindicated in patients who are hypersensitive to trimethoprim or any sulfa drug in the formulation
Pregnancy consideration:
Cotrimoxazole may cause harm to the developing fetus
Pregnant females should consult the physician before taking medicine as the potential benefits should outweigh the potential risks
Breastfeeding warnings: lactating females should not breastfeed during the medication
Breastfeeding should be recontinued 2 days after the last dose of cotrimoxazole
Pregnancy category:
Patient information leaflet
Generic Name: Cotrimoxazole
Pronounced: cot-ree-mox-a-zole
Why do we use Cotrimoxazole?
It helps treat various urinary tract bacterial infections, sepsis, diarrhea, STDs, and epididymitis.
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