Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Firmagon
(United States) [Available]Synonyms :
degarelix
Class :
Antineoplastics and GnRH Antagonist
Brand Name :
Firmagon
(United States) [Available]Synonyms :
degarelix
Class :
Antineoplastics and GnRH Antagonist
Dosage Forms & Strengths  Â
Powder for injection  Â
80mg  Â
120mg  Â
The initial dose was 240 mg as two subcutaneous injections of 120 mg each at a concentration of 40 mg per ml.
80 mg is given as the Maintenance Dose for one subcutaneous injection at a concentration of 20 mg per ml every 28 days
the first maintenance dose should be administered 28 days only after the initial dose
Dose Adjustments
Renal Dose Adjustments:
No adjustment is recommended for mild renal impairment (CrCl 50-80 ml per min)
Use with caution for moderate to severe renal impairment (CrCl <50 ml per min)
Liver Dose Adjustments:
No adjustment is recommended for mild to moderate Hepatic Impairment (Child-Pugh A and B)
Data not available and used with caution for Severe Hepatic Impairment (Child-Pugh C)
when both drugs are combined, there may be an increased risk or severity of QTC prolongation
when both drugs are combined, there may be an increased risk or severity of QTC prolongation
when both drugs are combined, there may be an increased risk or severity of QTC prolongation
when both drugs are combined, there may be an increased risk or severity of QTC prolongation
when both drugs are combined, there may be an increased risk or severity of QTC prolongation
it may enhance the qtc interval when combined with lofexidine
degarelix together with cisapride lead to an elevation of the QTc interval
QTc interval is increased both by lenvatinib and degarelix
when used together, entrectinib and degarelix both increase the QTc interval
when used together, encorafenib and degarelix both increase the QTc interval
It may enhance QTc interval when combined with pentamidine
when both drugs are combined, there may be an increased risk or severity of QTC prolongation
when both drugs are combined, there may be an increased risk or severity of QTC prolongation
when both drugs are combined, there may be an increased risk or severity of QTC prolongation
when both drugs are combined, there may be an increased risk or severity of QTC prolongation
when both drugs are combined, there may be an increased risk or severity of QTC prolongation
when both drugs are combined, there may be an increased risk or severity of QTC prolongation
when both drugs are combined, there may be an increased risk or severity of QTC prolongation
degarelix and loperamide are both known to elevate the QTc interval
When ponesimod is used together with degarelix, this leads to enhanced risk or seriousness of bradycardia
When degarelix is used together with adenosine, this leads to enhanced risk or seriousness of QTc prolongation
When degarelix is used together with givinostat, this leads to enhanced risk or seriousness of Qtc prolongation
methoxypolyethylene glycol-epoetin betaÂ
combining degarelix with methoxy polyethylene glycol-epoetin beta can raise the risk or severity of thrombosis
when both drugs are combined, both increase the QTC interval   
Adverse drug reaction  Â
Frequency defined   Â
>10%  Â
Elevated liver enzymes  Â
Hot flashes   Â
Injection site erythema  Â
Injection site pain  Â
Weight gain  Â
1-10%  Â
Arthralgia  Â
Back pain  Â
Fatigue  Â
HTN  Â
Injection site induration or swellingÂ
Pregnancy warnings:   Â
Breastfeeding warnings:Â
Pregnancy Categories:     Â
Patient Information Leaflet Â
Generic Name: degarelix (Rx)  Â
Pronounced: DEH-guh-REH-lixÂ
 Â
Why do we use degarelix?Â
degarelix is an anticancer drug used to treat advanced prostate cancers. This drug helps reduce the levels of testosterone hormone and prevents the spread of cancer cells.Â
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