Collaborative Artificial Intelligence in Acute Ischemic Stroke Diagnosis and Management
December 30, 2025
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Brand Name :
Ovicard, Prastova SR, CoeDHEA
Synonyms :
Dehydroepiandrosterone, Androstelone, GL701, Prasterone
Class :
Steroids
Brand Name :
Ovicard, Prastova SR, CoeDHEA
Synonyms :
Dehydroepiandrosterone, Androstelone, GL701, Prasterone
Class :
Steroids
Dosage forms & Strengths
Tablets
75mg
Vaginal insert
6.5mg
Dosage Forms & Strengths
Data not available
Refer to adult dosing
Action and Spectrum
DHEA is used as sex hormones, which are important for the growth and generation of healthy eggs, in female infertility treatment. It has a beneficial effect on immune response regulation. It also helps in conditions such as inflammation, cancer protective and neuro-protective activity.
Frequency defined
>10%
Vaginal discharge (14.2%)
1 to 10%
Weight fluctuation
Abnormal pap smear
0.1% to 1%
Uterine polyps
Cervical polyps
Benign breast mass
Breast cancer
Ovarian cancer
Frequency not defined
Pulmonary embolism
Erythema multiforme
Vascular purpura
Chloasma
Erythema nodosum
Gall bladder disease
Pancreatitis
Mood disorders
Black Box Warning
No special black box warnings are available
Contraindication/Caution:
Contraindication:
Breast cancer
Prostate cancer
Pregnancy
Lactation
Diabetes
Liver disease
Kidney disease
Caution:
Endometriosis
Ovarian cancer
Uterine cancer
PCOS
Uterine fibroids
Pregnancy consideration:
USFDA pregnancy category: Not assigned
Lactation:
Data about the excretion of dehydroepiandrosterone into breast milk is not known. It should be used with caution.
Pregnancy categories:
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.
<b>Category B: There was a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence, these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Pharmacology
DHEA acts as an androgen precursor helping in the sexual development of muscles and libido. It also helps in the neurodegenerative diseases.
Pharmacodynamics
The steroidal hormone is released by the adrenal cortex’s Zonareticularis in an age-related manner. In peripheral target tissues, these hormones undergo a transformation from inactive precursors into active sex steroids. These hormones are essential for most endocrine system-related biological activities as well as for energy and vigor. It is a 19-carbon steroid hormone that is lipophilic and may be transformed by the enzyme sulphotransferase found in the organ of the liver and adrenal gland.
Pharmacokinetics
Limited information is available regarding the ADME
Administration
It is administered orally, should be swallowed as a whole tablet along with meals.
Intravaginal insert of DHEA should be administered into the vaginal before going to bed.
Patient information leaflet
Generic Name: dehydroepiandrosterone
Why do we use dehydroepiandrosterone?
It is a hormone supplement that may increase sexual performance, reduce body fat, and strengthen bones. Elderly people or individuals with certain medical issues could benefit from it.
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