Indoor Tanning and Melanoma Risk: Molecular and Epidemiological Evidence
December 29, 2025
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Brand Name :
Cedilanide
Synonyms :
deslanoside
Class :
Cardiac Drugs
Dosage Forms & Strengths
Solution
1 mg
2 mg
Congestive Heart Failure (CHF)
Administer dose up to 1.6 mg intravenously as a single dose or in form of divided doses
Not suggested
Refer to adult dosing
When mometasone furoate is used together with deslanoside, this leads to enhanced risk or seriousness of adverse outcomes
When deslanoside is used together with oleandomycin, this leads to enhanced concentration serum of deslanoside
When deslanoside is used together with ridaforolimus, this leads to enhanced concentration serum of deslanoside
the potential or intensity of adverse effects can be heightened when flurandrenolide is combined with deslanoside
the cardiotoxic and arrhythmogenic activity of deslanoside may be increased
the risk of adverse effects may be increased
Actions and Spectrum
deslanoside exerts primarily through its influence on the sodium-potassium pump (Na+/K+ ATPase) in cardiac cells. This pump is responsible for maintaining the proper balance of sodium and potassium ions within the cells, which is crucial for the proper electrical activity and contraction of the heart muscle.
Frequency not defined
Nausea
Vomiting
Abdominal pain
Headache
Facial pain
Fatigue
Anorexia
Diarrhea
Weakness
Dizziness
Drowsiness
Disorientation
Mental confusion
Bad dreams
Delirium
Convulsions
Blurred vision
Gynecomastia
Vasoconstriction
Acute psychoses
Hallucinations
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: C
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
Elevated intracellular calcium concentrations enhance the contractile strength and force of cardiac muscle fibers.
This increased contractility is beneficial in conditions like congestive heart failure.
Pharmacodynamics
The inhibition of Na+/K+ ATPase results in an accumulation of intracellular sodium ions. This sodium accumulation indirectly affects the sodium-calcium exchanger, which normally exchanges one calcium ion for three sodium ions.
Pharmacokinetics
Absorption
deslanoside is administered intravenously thus it allows for rapid absorption of the drug directly into the bloodstream.
Distribution
deslanoside is distributed throughout the body.
Metabolism
deslanoside undergoes limited metabolism in the liver.
Elimination and excretion
The primary route of excretion for deslanoside is through the kidneys.
Administration
deslanoside is administered through intravenously (IV).
Patient information leaflet
Generic Name: deslanoside
Why do we use deslanoside?
deslanoside is used to treat congestive heart failure.
deslanoside is also used to manage certain types of irregular heart rhythms, particularly atrial fibrillation, and atrial flutter.
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