- March 15, 2022
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Brand Name :
Dexilant
Synonyms :
dexlansoprazole
Class :
Drugs for peptic ulcer & Proton pump inhibitors
30
mg
Orally
once a day
4 - 8
weeks
capsule
Duration can be modified according to symptom improvement in patients
Discontinuation of therapy every 6 to 12 months is recommended to avoid long-term therapy risk
Initial:
30
mg
Orally
once a day
8
weeks
Maintenance: If no improvements are seen in symptoms, increase the dose to 60 mg once a day after 4 weeks
gastro esophageal reflux disease (GERD)
For symptomatic non-erosive:
30
mg
Orally
once a day
4
weeks
Capsule
For erosive esophagitis with severe symptoms:
Initial: 60 mg orally once a day for 8 weeks
Maintenance: 30 mg orally once a day
gastro esophageal reflux disease (GERD)
Missed doses:
For missed doses, do not merge 2 doses at one time; take the next dose as scheduled by a physician
Dose Adjustments
30 mg orally once a day is recommended in case of moderate hepatic impairment
Terminate the therapy if severe hepatic impairment occurs
gastroesophageal reflux disease (GERD)
30
mg
Orally
every day
4
weeks
Children > 12 years and adolescents::
60
mg
Orally
once a day
8
weeks
Capsule
Maintenance of healing: 30 mg orally once a day
Children and adolescents >16 years:
80
mg
Orally
at bedtime
8
weeks
Capsule
gastro esophageal reflux disease (GERD)
Children > 12 years and adolescents:
30
mg
Orally
once a day
Capsule
Dose Adjustments
• 30 mg orally once a day is recommended in case of moderate hepatic impairment
Terminate the therapy if severe hepatic impairment occurs
gastroesophageal reflux disease (GERD)
Age: > 12 years:
30
mg
Orally
every day
4
weeks
when both drugs are combined, there may be a decrease in levels of serum concentration and absorption of erlotinib
may decrease the serum concentration
belumosudil: they may diminish the serum concentration of Inhibitors of the Proton Pump
may decrease the diagnostic effect of each other when combined
it may decrease the absorption of Levoketoconazole
may decrease the serum concentration
they decrease the concentration of active metabolites of infigratinib in the serum
may diminish the therapeutic effect of bisphosphonate derivative
may diminish the therapeutic effect of bisphosphonate derivative
may diminish the therapeutic effect of bisphosphonate derivative
may diminish the therapeutic effect of bisphosphonate derivative
may diminish the therapeutic effect of bisphosphonate derivatives
may diminish the therapeutic effect of bisphosphonate derivatives
may diminish the therapeutic effect of bisphosphonate derivatives
may diminish the therapeutic effect of bisphosphonate derivatives
may diminish the therapeutic effect of immune checkpoint inhibitors
may diminish the therapeutic effect of immune checkpoint inhibitors
may diminish the therapeutic effect of immune checkpoint inhibitors
Inhibitors of the Proton Pump: they may decrease the therapeutic effect of oral bisphosphonate derivatives
Inhibitors of the Proton Pump: they may decrease the therapeutic effect of oral bisphosphonate derivatives
Inhibitors of the Proton Pump: they may decrease the therapeutic effect of oral bisphosphonate derivatives
Inhibitors of the Proton Pump: they may decrease the therapeutic effect of oral bisphosphonate derivatives
Inhibitors of the Proton Pump: they may decrease the therapeutic effect of oral bisphosphonate derivatives
may enhance the concentration of serum when combined with dexlansoprazole
may enhance the concentration of serum when combined with dexlansoprazole
When bacampicillin is combined with dexlansoprazole, bacampicillin absorption and blood levels decrease by stomach acid reduction.
when both drugs are combined, there may be an increased risk of hypomagnesemia
Proton Pump inhibitors may increase the absorption of amphetamine
it may decrease the serum concentration of Atazanavir
l-methylfolate-pyridoxal 5′-phosphate-methylcobalamine
it may decrease the serum concentration of Multivitamins
it may decrease the serum concentration of Minerals
it may decrease the serum concentration of Minerals
it may decrease the serum concentration of Minerals
it may decrease the serum concentration of Minerals
it may decrease the serum concentration of Minerals
may increase the serum concentration of itraconazole
they decrease the efficacy of cysteamine
This could lead to a reduction in concentration serum of mycophenolate
blessed thistle by pharmacodynamic antagonism decreases the effect of dexlansoprazole
Frequency defined:
1%-10%
Acute myocardial infraction
Arrhythmia
Chest pain
Bradycardia
Hypertension
Tachycardia
Skin lesion
Skin rash
Urticaria
Acne vulgaris
Dermatitis
Change in libido
Goiter
Hypokalemia
Heavy menstrual bleeding
Abdominal distress
Abdominal pain
Frequency not defined:
Increased serum creatinine
Agitation
Anaphylaxis
Decreased white blood cell
Disorientation
Hepatic fibrosis
Anxiety
Hallucination
Hemolytic anemia
Pancytopenia
Urinary retention
Pregnancy consideration: No adverse effects have been reported in animal reproduction studies. It can be recommended for the treatment of GERD in pregnant women.
Lactation: Excretion of dexlansoprazole in breast milk is not known.
Pregnancy category:
Patient information leaflet
Generic Name: Dexlansoprazole
Pronounced: dex-lan-soe-pra-zole
Why do we use dexlansoprazole?
Dexlansoprazole is a proton pump inhibitor. It is used to decrease acid secretion in gastric parietal cells and treat esophagitis, acid reflux (GERD), and peptic ulcers.
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Founded in 2014, medtigo is committed to providing high-quality, friendly physicians, transparent pricing, and a focus on building relationships and a lifestyle brand for medical professionals nationwide.
MASSACHUSETTS – USA
60 Roberts Drive, Suite 313,
North Adams, MA 01247
MAHARASHTRA – INDIA
7, Shree Krishna, 2nd Floor,
Opp Kiosk Koffee,
Shirole Lane, Off FC Road,
Pune 411004, Maharashtra
