Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Alerpect
Synonyms :
dextropropoxyphene/dexchlorpheniramine maleate/bromhexine
Class :
Cough & Cold Preparations
Brand Name :
Alerpect
Synonyms :
dextropropoxyphene/dexchlorpheniramine maleate/bromhexine
Class :
Cough & Cold Preparations
Dosage Forms & Strengths
Syrup
100 ml
Shake the bottle well before use and take a dose as per physician advised
Not determined
Refer to adult dosing
Actions and Spectrum
dextropropoxyphene is an opioid analgesic, which means it acts on opioid receptors in the brain and spinal cord to relieve pain. It has both analgesic and antitussive properties.
dexchlorpheniramine maleate is an antihistamine and is used to relieve allergy symptoms such as sneezing, runny nose, itchy or watery eyes, and itching of the throat.
bromhexine is a mucolytic medication used to help loosen and thin mucus in the airways, making it easier to clear the mucus from the respiratory tract. It is used to manage respiratory conditions like cough associated with excessive mucus production.
Frequency not defined
Difficulty in urination
Dizziness
Nausea
Allergic reactions
Anorexia
Excitation
Fatigue
Gastric irritation
Insomnia
Dryness of mouth, nose, and throat
Epigastric distress
Diplopia
Euphoria
Nasal stuffiness
Physiological dependence
Restlessness
Nervousness
Sedation
Sleepiness
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
bromhexine should be used with caution in individuals with a history of gastric ulcers.
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:     
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
dextropropoxyphene works by binding opioid receptors in the brain and spinal cord. Activation of these receptors leads to various effects, including pain relief, and a sense of euphoria or relaxation.
dexchlorpheniramine maleate is an antihistamine. It works by blocking the action of histamine, a chemical released during allergic reactions. It also helps alleviate allergy symptoms such as sneezing, runny nose, and itching.
bromhexine is a mucolytic agent and it acts by thinning and loosening mucus in the airways, making it easier to cough up and clear from the respiratory tract. Thus, it can help relieve coughs associated with excessive mucus production in conditions like bronchitis.
Pharmacodynamics
dextropropoxyphene binding to mu opioid receptors results in pain relief. It changes the feeling of pain and reduces the transmission of pain signals in the brain and spinal cord.
dexchlorpheniramine maleate is an antihistamine and its pharmacodynamic effect acts by blocking of histamine receptors in the body. The histamine receptors which are blocked by dexchlorpheniramine maleate reduce the symptoms of allergies, such as itching, sneezing, runny nose, and hives.
bromhexine is a mucolytic agent and works by thinning and loosening of mucus in the respiratory tract. This helps in making mucus less viscous and easier to expel through coughing.
Pharmacokinetics
Limited information available on ADME.
Administration
dextropropoxyphene/dexchlorpheniramine maleate/bromhexine is a combination drug available in syrup form for oral intake.
Patient information leaflet
Generic Name: dextropropoxyphene/dexchlorpheniramine maleate/bromhexine
Why do we use dextropropoxyphene/dexchlorpheniramine maleate/bromhexine?
Alerpect (dextropropoxyphene/ dexchlorpheniramine maleate/bromhexine is a combination drug used to treat cough due to runny nose, and throat irritation. It is also used to provide relief from allergy symptoms such as sneezing, watery eyes, itching, swelling, and congestion or stiffness.
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