From Data to Decisions: Tailoring Treatment for Pituitary Tumors
February 3, 2026
Free CME credits
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Brand Name :
Apresol, Aprilife, Nepresol
Synonyms :
dihydralazine
Class :
Antihypertensive agents
Brand Name :
Apresol, Aprilife, Nepresol
Synonyms :
dihydralazine
Class :
Antihypertensive agents
Dosage Forms & Strengths
Tablet
25 mg
Take a dose of 12.5 mg orally two times daily
Maximum dose should not be more than 50 mg
Not determined
Refer to adult dosing
when bromazepam and dihydralazine are used together, there is a potential reduction in the bromazepam's metabolism
When dihydralazine is used together with somatotropin, this leads to a rise in dihydralazine metabolism
When dihydralazine is aided by hesperetin, it reduces hesperetin’s metabolism
Actions and Spectrum
Dihydralazine acts by directly relaxing the smooth muscles in the walls of arteries, leading to vasodilation.
The vasodilatory effect on the arterioles, resulting in decreased systemic vascular resistance.
Frequency not defined
Nausea
Palpitations
Headache
Increased heart rate
Diarrhea
Loss of appetite
Vomiting
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
Dihydralazine reduces systemic vascular resistance. This reduction in resistance facilitates blood flow and decreases the workload on the heart.
Pharmacodynamics
The heart rate may increase in response to the decrease in blood pressure, which helps to maintain adequate blood flow to tissues.
Pharmacokinetics
Absorption
Dihydralazine is absorbed from the gastrointestinal tract.
Distribution
Dihydralazine is distributed to various tissues.
Metabolism
Dihydralazine undergoes hepatic metabolism in the liver.
Elimination and excretion
Dihydralazine is excreted through the kidneys.
Administration
Dihydralazine is taken orally in form of tablet.
Patient information leaflet
Generic Name: dihydralazine
Why do we use dihydralazine?
Dihydralazine is used for the treatment of hypertension.
It is also used in combination with other drugs in the treatment of heart failure.
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
