Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Antabuse
Synonyms :
disulfiram
Class :
Drugs used in alcohol dependence, Psychiatry Agents
Brand Name :
Antabuse
Synonyms :
disulfiram
Class :
Drugs used in alcohol dependence, Psychiatry Agents
Dosage Forms & Strengths
Tablet
250mg
500mg
Safety and efficacy not studied
metronidazole (Topical): they may increase the adverse effect of disulfiram
it increases the toxicity of metronidazole by reducing metabolism
may enhance the toxic effects
may increase the toxic effect of tinidazole
may increase the toxic effect of Products Containing Ethanol
acetaminophen/doxylamine/dextromethorphan
may increase the anticholinergic effect of Anticholinergic Agents
may have an increasingly adverse effect when combined with disulfiram
benznidazole: they may increase the toxic effect of disulfiram
It may enhance toxicity when combined with cholic acid by diminishing the elimination
disulfiram can impact the hepatic/intestinal enzyme CYP3A4 metabolism, leading to an elevation in the level or potency of intranasal midazolam
it may enhance the metabolism when combined with oxcarbazepine
when ajmaline is used together with disulfiram, the risk or seriousness of QTc prolongation is enhanced
When disulfiram is used together with adenosine, this leads to enhanced risk or seriousness of QTc prolongation
When disulfiram is used together with givinostat, this leads to enhanced risk or seriousness of Qtc prolongation
Adverse drug reactions
Frequency Not Defined
Rash
Optic neuritis
Hepatitis
Impotence
Metallic aftertaste
Peripheral neuropathy
Fatigue
Headache
Acneiform eruptions
Polyneuritis
Pregnancy warnings:
AU TGA pregnancy category: B2
US FDA pregnancy category: Not assigned
Lactation:
Excreted into human milk is unknown
Pregnancy Categories:
Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester.
Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Patient Information Leaflet
Generic Name: disulfiram
Why do we use disulfiram?
disulfiram is a Drug used in alcohol dependence used to treat alcoholism.
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