drostanolone

Action and Spectrum

Actions and spectrum 

Drostanolone has anabolic properties; thus, it can stimulate protein synthesis and promote muscle growth.  

Drug Interaction

Adverse Reaction

Frequency not defined 

Facial hair  

Coarser skin 

Hypertriglyceridemia  

Hoarseness  

Coarser skin

Black Box Warning

 Black box warning 

None  

Contraindication / Caution

Contraindication/Caution:  

The drug is contraindicated in following situations: 

Hypersensitivity 

Prostate Cancer  

Breast Cancer 

Pregnancy / Lactation

Pregnancy Warnings:  

Pregnancy category: N/A  

Lactation:  

Excretion of the drug in human breast milk is unknown  

Pregnancy categories:    

Category A: Satisfactory and well-controlled studies show no evidence of risk to the fetus in the first trimester or in the later trimester.    

Category B: No evidence of risk to fetus found in animal reproduction studies and there are not enough studies on pregnant women.    

Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women.    

Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits.    

Category X: Drugs listed in this category clearly outweigh risks over benefits. These category drugs should be prohibited for pregnant women.    

Category N: There is no data available for the drug under this category. 

Pharmacology

Pharmacology:  

This drug is derived from dihydrotestosterone. It works by binding it to androgen receptors.  

Pharmacodynamics: 

The anabolic properties of drostanolone stimulate protein synthesis and promote skeletal muscle growth.  

Pharmacokinetics: 

Limited information is available on ADME.   

Adminstartion

Administration:  

It is administered into the muscles, i.e., intramuscular route, as an injection.  

Patient Information Leaflet

Patient information leaflet  

Generic Name: drostanolone  

Why do we use drostanolone?  

It is used to treat postmenopausal breast carcinoma. 

It gives a muscular appearance to the muscles due to its anabolic androgenic steroid class.