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Brand Name :
N/A
Synonyms :
Emzeltrectinib, emzeltrectinibum
Class :
Antineoplastic agent/TK (tyrosine kinase) inhibitor
Dosage Forms & StrengthsÂ
This drug is under clinical trial to study its efficacy against different types of cancer.
Dosage Forms & StrengthsÂ
Safety and efficacy study is not establishedÂ
Refer to adult dosingÂ
Actions and spectrum:Â
Emzeltrectinib acts by potentially inhibiting tyrosine kinase and thus produces an antineoplastic effect.Â
Frequency not definedÂ
Limited data availableÂ
Black Box WarningÂ
No special black box warnings are available for this drugÂ
Contraindication/Caution:Â
Contraindication:Â
Limited data availableÂ
Pregnancy/LactationÂ
Pregnancy consideration:Â
Safety and efficacy studies in pregnant women are not establishedÂ
Lactation:Â
Safety and efficacy studies in lactating mothers are not establishedÂ
Pregnancy category:Â
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.Â
Category B: There was a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence, these categories of drugs need to be avoided by pregnant women.Â
Category N: There is no data available for the drug under this categoryÂ
Pharmacology:Â
Emzeltrectinib is an antineoplastic drug.Â
Pharmacodynamics:Â
Emzeltrectinib inhibits tyrosine kinase potentially.Â
Pharmacokinetics:Â
The pharmacokinetic study of emzeltrectinib needs to be documented.Â
Administration:Â
Emzeltrectinib is an investigational drug, and it is to be administered as advised by the doctorÂ
Patient information leafletÂ
Generic Name: emzeltrectinibÂ
Why do we use emzeltrectinib?Â
Emzeltrectinib is under investigation for its use as an antineoplastic agent. This drug acts by inhibiting tyrosine kinase.Â