The Navigation Model of Therapy: Why Awareness Changes Everything
November 16, 2025
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Brand Name :
Vaseretic
Synonyms :
Class :
ACE inhibitors
Brand Name :
Vaseretic
Synonyms :
Class :
ACE inhibitors
Dosage Forms & Strengths
Tablet
5mg/12.5mg- enalapril/hydrochlorothiazide
10mg/12.5mg- enalapril/hydrochlorothiazide
10-40 mg/12.5-50 mg enalapril/hydrochlorothiazide orally every day
Adverse drug reactions:
Frequency Defined
1-10%
Enalapril
Hypotension (0.9-6.7%)
Cough (1-2%)
Rash (1.5%)
Headache (2-5%)
Chest pain (2%)
Dizziness (4-8%)
Hydrochlorothiazide
Hypotension
Anorexia
Hypokalemia
Phototoxicity
Epigastric distress
Post marketing Reports
Hydrochlorothiazide
Non-melanoma skin cancer
Pregnancy warnings:
AU TGA pregnancy category: D
US FDA pregnancy category: D
Lactation:
Excreted into human milk is known (enalapril); known (hydrochlorothiazide)
Pregnancy Categories:
Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester.
Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Patient Information Leaflet
Generic Name: enalapril/hydrochlorothiazide
Why do we use enalapril/hydrochlorothiazide?
enalapril/hydrochlorothiazide are an ACE inhibitor used to treat hypertension.
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