Cystathionine γ-Lyase Identified as a Key Regulator of Memory and Learning
January 1, 2026
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Brand Name :
Enos, Enclopure, Enclowin, Ovafree, Enfin
Synonyms :
enclomiphene
Class :
Selective Estrogen Receptor Modulator
Brand Name :
Enos, Enclopure, Enclowin, Ovafree, Enfin
Synonyms :
enclomiphene
Class :
Selective Estrogen Receptor Modulator
Dosage Forms & Strengths
Tablet
25 mg
50 mg
Take a dose of 50 mg orally once daily
Not determined
Refer to adult dosing
Actions and Spectrum
enclomiphene is used to induce ovulation in women who have ovulatory disorders or irregular menstrual cycles.
By promoting the release of LH and FSH, it helps trigger the maturation and release of eggs from the ovaries, which can enhance fertility.
Frequency not defined
Hot flashes
Metrorrhagia
Breast discomfort
Vomiting
Bloating
Enlarged ovary
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
enclomiphene is classified as a selective estrogen receptor modulator (SERM). It acts as an antagonist at estrogen receptors in certain tissues, including the hypothalamus and pituitary gland, leading to reduced negative feedback of estrogen on these tissues.
enclomiphene inhibits the negative feedback of estrogen on the hypothalamus and pituitary gland.
Pharmacodynamics
enclomiphene reduces the negative feedback of estrogen on the hypothalamus and pituitary gland. This effect leads to an increase in gonadotropin-releasing hormone (GnRH) production and secretion from the hypothalamus.
Pharmacokinetics
Absorption
enclomiphene is readily absorbed from the gastrointestinal tract after oral intake.
Distribution
enclomiphene is distributed throughout the body.
Metabolism
enclomiphene undergoes hepatic metabolism in the liver.
Elimination and excretion
enclomiphene are excreted through the feces.
Administration
enclomiphene is taken orally in the form of tablets.
Patient information leaflet
Generic Name: enclomiphene
Why do we use enclomiphene?
enclomiphene is used in women with anovulatory infertility, which means they have irregular or absent ovulation.
It may also use as the first-line treatment for women with conditions like polycystic ovary syndrome (PCOS) or unexplained infertility who do not ovulate regularly.
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