etamsylate

Action and Spectrum

Actions and Spectrum 

etamsylate acts as a hemostatic agent, which means it helps in the formation of blood clots to stop bleeding.  

They can increase platelet adhesion, which is important for the formation of a stable blood clot. 

Drug Interaction

Adverse Reaction

Frequency not defined  

Hypotension 

Nausea 

Vomiting   

Abdominal pain   

Asthenia  

Headache

Black Box Warning

Black Box Warning 

None 

Contraindication / Caution

Contraindication/Caution: 

Contraindication: 

• etamsylate should not be used in individuals who have a known hypersensitivity or allergy to etamsylate or any of its components. 

Caution: 

• etamsylate should be used with caution in pregnant or breastfeeding women. 
• Caution should be taken while using etamsylate in combination with anticoagulant drugs.

Pregnancy / Lactation

Pregnancy consideration: 

Pregnancy category: N/A 

Lactation: Excretion into human milk is unknown  

Pregnancy Categories:         

Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester. 

Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.  

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women. 

Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits. 

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women. 

Category N: There is no data available for the drug under this category. 

Pharmacology

Pharmacology  

etamsylate enhances the function of platelets, which are blood cells responsible for forming blood clots.  

etamsylate helps reduce capillary fragility, making the small blood vessels less prone to leakage and bleeding. 

Pharmacodynamics 

etamsylate has mild vasoconstrictor properties, particularly in small blood vessels.  

Vasoconstriction refers to the narrowing of blood vessels, which can help reduce blood flow to the site of bleeding and contribute to hemostasis. 

Pharmacokinetics 

Absorption   

etamsylate is well-absorbed from the gastrointestinal tract after oral administration.  

Distribution 

etamsylate is distributed throughout the body. 

Metabolism 

etamsylate undergoes minimal metabolism in the liver. 

Elimination and excretion 

etamsylate is excreted through the kidneys. 

Adminstartion

Administration 

etamsylate taken orally in tablet form also it administered as intravenous (IV) or an intramuscular (IM) injection.

Patient Information Leaflet

Patient information leaflet 

Generic Name: etamsylate 

Why do we use etamsylate? 

etamsylate is used to treat menorrhagia as this can help reduce excessive menstrual bleeding and alleviate associated symptoms.  

etamsylate is used in certain bleeding disorders, such as thrombocytopenia and capillary fragility disorders, to prevent bleeding episodes.