2025 Guidelines for the Evaluation and Management of Adults With Congenital Heart Disease
December 19, 2025
Free CME credits
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Brand Name :
Alstat, Bloc, Botrostat, Capilyte, Cosklot, Disylate, Cotham, Dicynene, Amilate
Synonyms :
etamsylate
Class :
Haemostatics
Brand Name :
Alstat, Bloc, Botrostat, Capilyte, Cosklot, Disylate, Cotham, Dicynene, Amilate
Synonyms :
etamsylate
Class :
Haemostatics
Dosage Forms & Strengths
Tablet
500 mg
Solution
250 mg
Take a dose of 500 mg orally three times daily for ten days and starting five days prior to the onset of menstruation
Diffuse perioperative haemorrhage
As preoperative: Dose of 500 mg given orally 1 hour before surgery
As postoperative: Take a dose of 500 mg orally in 4 to 6 hourly as long as bleeding risk continue
Acute capillary haemorrhage
Administer dose of 500 to 750 mg three times daily through intravenously or intramuscularly
Not determined
Refer to adult dosing
Actions and Spectrum
etamsylate acts as a hemostatic agent, which means it helps in the formation of blood clots to stop bleeding.
They can increase platelet adhesion, which is important for the formation of a stable blood clot.
Frequency not defined
Hypotension
Nausea
Vomiting
Abdominal pain
Asthenia
Headache
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
etamsylate enhances the function of platelets, which are blood cells responsible for forming blood clots.
etamsylate helps reduce capillary fragility, making the small blood vessels less prone to leakage and bleeding.
Pharmacodynamics
etamsylate has mild vasoconstrictor properties, particularly in small blood vessels.
Vasoconstriction refers to the narrowing of blood vessels, which can help reduce blood flow to the site of bleeding and contribute to hemostasis.
Pharmacokinetics
Absorption
etamsylate is well-absorbed from the gastrointestinal tract after oral administration.
Distribution
etamsylate is distributed throughout the body.
Metabolism
etamsylate undergoes minimal metabolism in the liver.
Elimination and excretion
etamsylate is excreted through the kidneys.
Administration
etamsylate taken orally in tablet form also it administered as intravenous (IV) or an intramuscular (IM) injection.
Patient information leaflet
Generic Name: etamsylate
Why do we use etamsylate?
etamsylate is used to treat menorrhagia as this can help reduce excessive menstrual bleeding and alleviate associated symptoms.
etamsylate is used in certain bleeding disorders, such as thrombocytopenia and capillary fragility disorders, to prevent bleeding episodes.
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
