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December 27, 2025
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Brand Name :
N/A
Synonyms :
Ethacizine
Class :
Antiarrhythmic agent
Brand Name :
N/A
Synonyms :
Ethacizine
Class :
Antiarrhythmic agent
Dosage Forms & Strengths
Refractory ventricular and supraventricular arrhythmias
Take an initial dose of 50 mg orally for 2 to 3 times daily
Take an initial dose of 50 mg orally for 2 to 3 times daily
Not determined
Action and Spectrum:
These agents treat cardiac arrhythmias by influencing the polarization-repolarization phase of the action potential, its refractoriness, and membrane responsiveness within cardiac fibers.
Adverse reaction
None
Black box warning:
None
Contraindications/caution:
None
Pregnancy Warnings:
Pregnancy category: N/A
Lactation: Excretion of the drug into the human breast milk is unknown
Pregnancy categories:
Category A: Satisfactory and well-controlled studies show no evidence of risk to the fetus in the first trimester or in the later trimester.
Category B: No evidence of risk to fetus found in animal reproduction studies and there are not enough studies on pregnant women.
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women.
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits.
Category X: Drugs listed in this category clearly outweigh risks over benefits. These category drugs should be prohibited for pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
Ethacizine is a drug classified as an antiarrhythmic agent which closely related to moricizine drug.
Pharmacodynamics
Ethacizine is used to prevent the depolarizing current responsible for intra-atrial and His-Purkinje-ventricular conduction.
Pharmacokinetics:
Data on ADME is not available.
Administration:
It is administered orally.
Patient information leaflet
Generic Name: Ethacizine
Why do we use Ethacizine?
Ethacizine is used in Russian countries for the treatment of severe or refractory ventricular and supraventricular arrhythmias.
It is also indicated in the treatment of refractory tachycardia associated with Wolff-Parkinson-White syndrome.
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