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Brand Name :
N/A
Synonyms :
Ethohexadiol; 2-Ethyl-1,3-hexanediol
Class :
Pesticides, Obsolete pesticides, Insect repellents
Dosage Forms & Strengths Â
Insect repellent (off-label)
Applied directly to the skin or garments
Guide for In Vitro Use:
CHO (Chinese Hamster ovary) cells (HGPT locus) were subjected to a forward gene mutation assay with a dose range of 1.0-4.5 mg/ml
Although this usually doesn't cause skin irritation, it can cause chemical conjunctivitis
It works as a typical insect repellent for mosquitoes, black flies, chiggers, and other biting ins:
Dose Adjustments
N/A
Not indicatedÂ
Refer to the adult dosingÂ
Actions and Spectrum: Â
Actions: Â
Eto hexadiol is an ectoparasiticide used widely in various industries and households. It is a liquid alcohol, serving as a solvent, chelating agent, and part of cosmetic formulations. It was previously used as an insect repellent.Â
Spectrum: Â
Eto hexadiol dissolves both active and non-active substances, used in personal care products like hair tonics and cleaning solutions, and in sunscreen manufacturing. It repels insects at high concentrations and is used in perfumery.Â
Frequency not defined Â
Chemical Conjunctivitis Â
Black Box Warning: Â
Keep this out of reach of children. Â
Contraindication/Caution: Â
Contraindications Â
Hypersensitivity Â
Cautions Â
Kidney diseaseÂ
Liver diseaseÂ
Drug interactions Â
Pregnancy & Breastfeeding Â
Pregnancy/LactationÂ
Pregnancy consideration:  Â
No data is available regarding the administration of the drug during pregnancy. Â
Breastfeeding warnings:  Â
No data is available regarding the excretion of drug in breast milk. Â
Pregnancy category: Â
Category A: Well-controlled and satisfactory studies show no risk to the fetus in the first or later trimester. Â
<b>Category B: There was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. Â
Category C: There was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.    Â
Category D: Adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.    Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.    Â
Category N: No data is available for the drug under this category. Â
Pharmacology: Â
Etohexadiol, or ethohexadiol, is an ectoparasiticide and insect repellent which is also known as “Rutgers 612” or “6-12.Â
Pharmacodynamics: Â
N/A Â
Pharmacokinetics: Â
Absorption Â
The drug is absorbed through the skin. Â
Excretion and EliminationÂ
Excreted through kidneys.Â
Administration: Â
Applied directly to the skin or garments Â
Patient information leaflet Â
Generic Name: etohexadiol Â
Pronounced: ee-toh-hek-suh-die-ol Â
Why do we use etohexadiol? Â
Ethyl hexanediol (etohexadiol) has wide-ranging uses in various industries and consumer products. It serves as a a chelating agent in medicine & used in printing ink, & a plasticizer & insect repellent. It’s also utilized in cosmetics, chemical sealants, adhesives, coatings, toners, colorants, and in agriculture as a repellent, insect attractant, and chemosterilant.Â