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Brand Name :
Vabysmo, faricimab-svoa
Synonyms :
Faricimab
Class :
Monoclonal antibody
Dosage Forms & Strengths
Injectable solution
120mg/ml
Age-related Neovascular Macular Degeneration
6
mg
Solution
intravitreal injection
every four weeks
for the first four doses
Followed by weeks 8 and 12
Dosage regimen
At weeks 22 and 44, administer 6mg by intravitreal injection
At weeks 24,36 and 48, administer 6mg by intravitreal injection
At weeks 20,28,36 and 44, administer 6mg by intravitreal injection
Regimen 1:
6mg every four weeks by intravitreal injection for the first four doses
Regimen 2:
6mg every four weeks by intravitreal injection for the first six doses
Dosage Forms & Strengths
Safety and efficacy not established
Refer adult dosing
Frequency defined:
1-10%
ARMD
Vitreous floaters
Increased intraocular pressure
Intraocular inflammation
Ocular discomfort
Conjunctival hemorrhage
Retinal pigment epithelial tears
Eye pain
Eye irritation
DME
Vitreous floaters
Eye pain
Eye irritation
Vitreous hemorrhage
Conjunctival hemorrhage
Increased intraocular pressure
Intraocular inflammation
Ocular discomfort
Pregnancy consideration: Insufficient data available
Lactation: Excretion of the drug in human breast milk is unknown
Pregnancy category:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Patient information leaflet
Generic Name: faricimab
Pronounced: (far-IK-i-mab)
Why do we use faricimab?
It is used to treat diabetic macular edema and age-related macular degeneration.