A Game-Changer for Diabetes: Polymer Delivers Insulin Painlessly Through Skin
November 25, 2025
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Brand Name :
Vabysmo, faricimab-svoa
Synonyms :
Faricimab
Class :
Monoclonal antibody
Brand Name :
Vabysmo, faricimab-svoa
Synonyms :
Faricimab
Class :
Monoclonal antibody
Dosage Forms & StrengthsÂ
Injectable solutionÂ
120mg/mlÂ
Age-related Neovascular Macular DegenerationÂ
6
mg
Solution
intravitreal injection
every four weeks
for the first four doses
Followed by weeks 8 and 12
Dosage regimen
At weeks 22 and 44, administer 6mg by intravitreal injection
At weeks 24,36 and 48, administer 6mg by intravitreal injection
At weeks 20,28,36 and 44, administer 6mg by intravitreal injection
Regimen 1:
6mg every four weeks by intravitreal injection for the first four doses
Regimen 2:
6mg every four weeks by intravitreal injection for the first six doses
Dosage Forms & StrengthsÂ
Safety and efficacy not establishedÂ
Refer adult dosingÂ
Frequency defined:Â Â
1-10%Â
ARMDÂ
Vitreous floatersÂ
Increased intraocular pressureÂ
Intraocular inflammationÂ
Ocular discomfortÂ
Conjunctival hemorrhageÂ
Retinal pigment epithelial tearsÂ
Eye painÂ
Eye irritationÂ
DMEÂ
Vitreous floatersÂ
Eye painÂ
Eye irritationÂ
Vitreous hemorrhageÂ
Conjunctival hemorrhageÂ
Increased intraocular pressureÂ
Intraocular inflammationÂ
Ocular discomfortÂ
Pregnancy consideration: Insufficient data availableÂ
Lactation: Excretion of the drug in human breast milk is unknown Â
Pregnancy category:Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.  Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.   Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.   Â
Category N: There is no data available for the drug under this categoryÂ
Patient information leafletÂ
Generic Name: faricimabÂ
Pronounced: (far-IK-i-mab)Â
Why do we use faricimab?Â
It is used to treat diabetic macular edema and age-related macular degeneration.Â
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